Novel AI driven approach to classify infant motor functions.

Journal: Scientific reports
PMID:

Abstract

The past decade has evinced a boom of computer-based approaches to aid movement assessment in early infancy. Increasing interests have been dedicated to develop AI driven approaches to complement the classic Prechtl general movements assessment (GMA). This study proposes a novel machine learning algorithm to detect an age-specific movement pattern, the fidgety movements (FMs), in a prospectively collected sample of typically developing infants. Participants were recorded using a passive, single camera RGB video stream. The dataset of 2800 five-second snippets was annotated by two well-trained and experienced GMA assessors, with excellent inter- and intra-rater reliabilities. Using OpenPose, the infant full pose was recovered from the video stream in the form of a 25-points skeleton. This skeleton was used as input vector for a shallow multilayer neural network (SMNN). An ablation study was performed to justify the network's architecture and hyperparameters. We show for the first time that the SMNN is sufficient to discriminate fidgety from non-fidgety movements in a sample of age-specific typical movements with a classification accuracy of 88%. The computer-based solutions will complement original GMA to consistently perform accurate and efficient screening and diagnosis that may become universally accessible in daily clinical practice in the future.

Authors

  • Simon Reich
    University Medical Center Göttingen, Child and Adolescent Psychiatry and Psychotherapy, 37075, Göttingen, Germany.
  • Dajie Zhang
    University Medical Center Göttingen, Child and Adolescent Psychiatry and Psychotherapy, 37075, Göttingen, Germany.
  • Tomas Kulvicius
    University Medical Center Göttingen, Child and Adolescent Psychiatry and Psychotherapy, 37075, Göttingen, Germany.
  • Sven Bölte
    Department of Women's and Children's Health, Karolinska Institutet, Center of Neurodevelopmental Disorders (KIND), 113 30, Stockholm, Sweden.
  • Karin Nielsen-Saines
    University of California, David Geffen School of Medicine, Los Angeles, CA, 90095, USA.
  • Florian B Pokorny
    Division of Phoniatrics, Research Unit interdisciplinary Developmental Neuroscience, Medical University of Graz, 8036, Graz, Austria.
  • Robert Peharz
    Department of Mathematics and Computer Science, Eindhoven University of Technology, 5600 MB, Eindhoven, The Netherlands.
  • Luise Poustka
    Department of Child and Adolescent Psychiatry and Psychotherapy, University Medical Centre Göttingen, von-Siebold-Str. 5, 37075 Göttingen, Germany.
  • Florentin Wörgötter
    Department of Computational Neuroscience, Georg-August-University, Friedrich-Hund Platz, 1, 37077, Göttingen, Germany.
  • Christa Einspieler
    Division of Phoniatrics, Research Unit interdisciplinary Developmental Neuroscience, Medical University of Graz, 8036, Graz, Austria.
  • Peter B Marschik
    University Medical Center Göttingen, Child and Adolescent Psychiatry and Psychotherapy, 37075, Göttingen, Germany. peter.marschik@med.uni-goettingen.de.