Evaluation of the potential nephrotoxicity and mechanism in rats after long-term exposure to the traditional Tibetan medicine tsothel.

Journal: Pharmaceutical biology
Published Date: Dec 1, 2018

Abstract

CONTEXT: Tsothel, a traditional Tibetan medicine, is regarded as 'the king of essences'. Nevertheless, tsothel has aroused serious concern regarding its biosafety because its main component is HgS. Unfortunately, toxicological studies on tsothel are scarce.

Authors

  • Li Xiang
    a College of Pharmacy , Chengdu University of Traditional Chinese Medicine , Chengdu , P.R. China.
  • Bo Lin
    b Pharmaceutical Department , The Second Affiliated Hospital of Hainan Medical University , Haikou , P.R. China.
  • Ping Wang
    School of Chemistry and Chemical Engineering, Shandong University of Technology, 255049, Zibo, PR China. Electronic address: wangping876@163.com.
  • Yingfan Hu
    a College of Pharmacy , Chengdu University of Traditional Chinese Medicine , Chengdu , P.R. China.
  • Jiasi Wu
    a College of Pharmacy , Chengdu University of Traditional Chinese Medicine , Chengdu , P.R. China.
  • Yong Zeng
    a College of Pharmacy , Chengdu University of Traditional Chinese Medicine , Chengdu , P.R. China.
  • Xianli Meng
    a College of Pharmacy , Chengdu University of Traditional Chinese Medicine , Chengdu , P.R. China.

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