Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency, and liver failure.

Journal: Nutrition (Burbank, Los Angeles County, Calif.)
PMID: 30682545

Abstract

OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care unit (ICU) has not been fully elucidated. The aim of this study was to investigate whether the serum concentrations of 25-hydroxyvitamin D (25[OH]D) within the first 48 h after ICU admission are associated with prognostic indicators (Acute Physiology and Chronic Health Evaluation [APACHE] II, Sequential Organ Failure Assessment [SOFA] score, Charlson comorbidity index [CCI]), clinical complications, serum C-reactive protein (CRP) concentrations, mechanical ventilation duration, and mortality.

Authors

  • Tatyanne Ln Gomes
    Clinical Hospital, Empresa Brasileira de Serviços Hospitalares, Federal University of Goias, Goiânia, Brazil.
  • Renata C Fernandes
    Clinical Hospital, Empresa Brasileira de Serviços Hospitalares, Federal University of Goias, Goiânia, Brazil.
  • Liana L Vieira
    Clinical Hospital, Empresa Brasileira de Serviços Hospitalares, Federal University of Goias, Goiânia, Brazil.
  • Raquel M Schincaglia
    Clinical and Sports Nutrition Research Laboratory, Faculty of Nutrition, Federal University of Goias, Goiânia, Brazil.
  • João F Mota
    Clinical and Sports Nutrition Research Laboratory, Faculty of Nutrition, Federal University of Goias, Goiânia, Brazil.
  • Marciano S Nóbrega
    Clinical Hospital, Empresa Brasileira de Serviços Hospitalares, Federal University of Goias, Goiânia, Brazil.
  • Claude Pichard
    Clinical Nutrition, Geneva University Hospital, Geneva, Switzerland.
  • Gustavo D Pimentel
    Clinical and Sports Nutrition Research Laboratory, Faculty of Nutrition, Federal University of Goias, Goiânia, Brazil. Electronic address: gupimentel@yahoo.com.br.

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