[Downregulation of PTTG1 expression inhibits the proliferation and invasiveness and promotes the apoptosis of human prostate cancer LNCaP-AI cells].

Journal: Zhonghua nan ke xue = National journal of andrology
PMID: 29723450

Abstract

OBJECTIVE: To investigate the effects of down-regulation of PTTG1 expression on the proliferation, invasiveness and apoptosis of androgen-independent human prostate cancer LNCaP-AI cells and their sensitivity to androgen antagonists.

Authors

  • Xi-Liang Cao
    Department of Urology, Xuzhou First People's Hospital, Xuzhou, Jiangsu 221004, China.
  • Yang-Yang Wei
    Department of Urology, Anhui Armed Police Corps Hospital, Hefei, Anhui 230061, China.
  • Xiao-Ming Song
    Department of Urology, The 71st Group Army Hospital of the PLA, Xuzhou, Jiangsu 221004, China.
  • Ke-Quan Lu
    Center for Tumor Treatment, The 71st Group Army Hospital of the PLA, Xuzhou, Jiangsu 221004, China.
  • Wen-Chao Yu
    Department of Urology, Huaihai Hospital of Bengbu Medical College / the 97th Hospital of PLA, Xuzhou, Jiangsu 221004, China..
  • Yong-Qiang Chen
    Center for Tumor Treatment, Huaihai Hospital of Bengbu Medical College / the 97th Hospital of PLA, Xuzhou, Jiangsu 221004, China.
  • Yong-Liang Liu
    Department of Urology, Huaihai Hospital of Bengbu Medical College / the 97th Hospital of PLA, Xuzhou, Jiangsu 221004, China..
  • Jiang-Ping Gao
    Department of Urology, General Hospital of PLA, Beijing, 100086, China.

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