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[Down-regulated PTTG1 expression promotes the senescence of human prostate cancer LNCaP-AI].

Zhonghua nan ke xue = National journal of andrology 32216239
OBJECTIVE: To investigate the effect of the down-regulated expression of pituitary tumor-transforming gene 1 (PTTG1) on the senescence of human castration-resistant prostate cancer LNCaP-AI cells.
beta-Galactosidase Cell Line, Tumor Cell Proliferation Humans Male Prostatic Neoplasms, Castration-Resistant RNA, Small Interfering Securin
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[Downregulation of PTTG1 expression inhibits the proliferation and invasiveness and promotes the apoptosis of human prostate cancer LNCaP-AI cells].

Zhonghua nan ke xue = National journal of andrology 29723450
OBJECTIVE: To investigate the effects of down-regulation of PTTG1 expression on the proliferation, invasiveness and apoptosis of androgen-independent human prostate cancer LNCaP-AI cells and their sensitivity to androgen antagonists.
Androgen Antagonists Apoptosis Cell Line, Tumor Cell Proliferation Down-Regulation Humans Male Neoplasm Invasiveness Prostatic Neoplasms RNA, Small Interfering Securin Time Factors Transfection
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