AIMC Topic: Securin

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[Down-regulated PTTG1 expression promotes the senescence of human prostate cancer LNCaP-AI].

Zhonghua nan ke xue = National journal of andrology Mar 1, 2019
OBJECTIVE: To investigate the effect of the down-regulated expression of pituitary tumor-transforming gene 1 (PTTG1) on the senescence of human castration-resistant prostate cancer LNCaP-AI cells.
Humans Male Cell Line, Tumor Cell Proliferation RNA, Small Interfering Prostatic Neoplasms, Castration-Resistant Securin beta-Galactosidase
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[Downregulation of PTTG1 expression inhibits the proliferation and invasiveness and promotes the apoptosis of human prostate cancer LNCaP-AI cells].

Zhonghua nan ke xue = National journal of andrology Jul 1, 2017
OBJECTIVE: To investigate the effects of down-regulation of PTTG1 expression on the proliferation, invasiveness and apoptosis of androgen-independent human prostate cancer LNCaP-AI cells and their sensitivity to androgen antagonists.
Humans Male Time Factors Cell Line, Tumor Cell Proliferation Apoptosis Neoplasm Invasiveness Prostatic Neoplasms Androgen Antagonists RNA, Small Interfering Transfection Securin Down-Regulation
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