Deep-Learning for Epicardial Adipose Tissue Assessment With Computed Tomography: Implications for Cardiovascular Risk Prediction.

Journal: JACC. Cardiovascular imaging
PMID:

Abstract

BACKGROUND: Epicardial adipose tissue (EAT) volume is a marker of visceral obesity that can be measured in coronary computed tomography angiograms (CCTA). The clinical value of integrating this measurement in routine CCTA interpretation has not been documented.

Authors

  • Henry W West
    Acute Multidisciplinary Imaging and Interventional Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Muhammad Siddique
    Acute Multidisciplinary Imaging and Interventional Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Caristo Diagnostics Pty Ltd, Oxford, United Kingdom.
  • Michelle C Williams
    British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Chancellor's Building, 49 Little France Cres, Edinburgh, UK.
  • Lucrezia Volpe
    Acute Multidisciplinary Imaging and Interventional Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Ria Desai
    Northwestern University, Evanston, Illinois, USA.
  • Maria Lyasheva
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, UK.
  • Sheena Thomas
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, UK.
  • Katerina Dangas
    Acute Multidisciplinary Imaging and Interventional Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Christos P Kotanidis
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, UK.
  • Pete Tomlins
    Acute Multidisciplinary Imaging and Interventional Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom; Caristo Diagnostics Pty Ltd, Oxford, United Kingdom.
  • Ciara Mahon
    Royal Brompton and Harefield National Health Service (NHS) Foundation Trust, London, United Kingdom.
  • Attila Kardos
    Translational Cardiovascular Research Group, Department of Cardiology, Milton Keynes University Hospital, Milton Keynes, United Kingdom; Faculty of Medicine and Health Sciences, University of Buckingham, Buckingham, United Kingdom.
  • David Adlam
    Department of Cardiovascular Sciences and National Institute for Health Research Leicester Biomedical Research Centre, University of Leicester, Leicester, United Kingdom.
  • John Graby
    Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom.
  • Jonathan C L Rodrigues
    Dept of Radiology, Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.
  • Cheerag Shirodaria
    Department of Cardiology, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, UK.
  • John Deanfield
    National Centre for Cardiovascular Prevention and Outcomes, Institute of Cardiovascular Science, University College London, 1 St Martins Le Grand, London, UK.
  • Nehal N Mehta
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland. Electronic address: nehal.mehta@nih.gov.
  • Stefan Neubauer
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Keith M Channon
    Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford, UK.
  • Milind Y Desai
    Heart and Vascular Institute Cleveland Clinic, Cleveland, OH, USA.
  • Edward D Nicol
    Departments of Cardiology and Radiology, Royal Brompton Hospital, Guys and St Thomas' NHS Foundation Trust, London, UK; School of Biomedical Engineering and Imaging Sciences, King's College, London, UK. Electronic address: e.nicol@nhs.net.
  • David E Newby
    Edinburgh Imaging Facility QMRI, Edinburgh, EH16 4TJ, UK; Centre for Cardiovascular Science, Edinburgh, EH16 4TJ, UK.
  • Charalambos Antoniades
    Acute Multidisciplinary Imaging and Interventional Centre, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.