The Economic Burden of ACPA-Positive Status Among Patients with Rheumatoid Arthritis.
Journal:
Journal of managed care & specialty pharmacy
PMID:
29290168
Abstract
BACKGROUND: Anticitrullinated protein antibodies (ACPAs) are serological biomarkers associated with early, rapidly progressing rheumatoid arthritis (RA), including more severe disease and joint damage. ACPA testing has become a routine tool for RA diagnosis and prognosis. Furthermore, treatment efficacy has been shown to vary by ACPA-positive status. However, it is not clear if the economic burden of patients with RA varies by ACPA status.