Deep learning MRI-only synthetic-CT generation for pelvis, brain and head and neck cancers.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PMID:

Abstract

BACKGROUND AND PURPOSE: MRI-only planning relies on dosimetrically accurate synthetic-CT (sCT) generation to allow dose calculation. Here we validated the dosimetric accuracy of sCTs generated using a deep learning algorithm for pelvic, brain and head and neck (H&N) cancer sites using variable MRI data from multiple scanners.

Authors

  • David Bird
    Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, United Kingdom; Radiotherapy Research Group, Leeds Institute of Medical Research, University of Leeds, United Kingdom. Electronic address: David.bird3@nhs.net.
  • Richard Speight
    Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, United Kingdom.
  • Sebastian Andersson
    RaySearch AB, Stockholm, Sweden.
  • Jenny Wingqvist
    RaySearch AB, Stockholm, Sweden.
  • Bashar Al-Qaisieh
    Leeds Cancer Centre, Leeds Teaching Hospitals NHS Trust, United Kingdom.