Impact of glioma metabolism-related gene ALPK1 on tumor immune heterogeneity and the regulation of the TGF-β pathway.

Journal: Frontiers in immunology
PMID:

Abstract

BACKGROUND: Recent years have seen persistently poor prognoses for glioma patients. Therefore, exploring the molecular subtyping of gliomas, identifying novel prognostic biomarkers, and understanding the characteristics of their immune microenvironments are crucial for improving treatment strategies and patient outcomes.

Authors

  • YaoFeng Hu
    Department of Neurological Care Unit, The First Affiliated Hospital of YangTze University, Jingzhou, Hubei, China.
  • Sen Qin
    Department of Orthopedics, The First Affiliated Hospital of YangTze University, Jingzhou, Hubei, China.
  • RuCui Deng
    Department of Neurological Care Unit, The First Affiliated Hospital of YangTze University, Jingzhou, Hubei, China.