Machine Learning Identify Ferroptosis-Related Genes as Potential Diagnostic Biomarkers for Gastric Intestinal Metaplasia.

Journal: Technology in cancer research & treatment
PMID: 39169865

Abstract

BACKGROUND: Gastric intestinal metaplasia(GIM) is an independent risk factor for GC, however, its pathogenesis is still unclear. Ferroptosis is a new type of programmed cell death, which may be involved in the process of GIM. The purpose of this study was to analyze the expression of ferroptosis-related genes (FRGs) in GIM tissues and to explore the relationship between ferroptosis and GIM.

Authors

  • Tingting Li
    Key Laboratory of Biotechnology and Bioresources Utilization (Dalian Minzu University), Ministry of Education, Dalian, China.
  • Qi Yang
    Department of Radiology, The First Hospital of Jilin University, No.1, Xinmin Street, Changchun 130021, China (Y.W., M.L., Z.M., J.W., K.H., Q.Y., L.Z., L.M., H.Z.).
  • Yun Liu
    Google Health, Palo Alto, CA USA.
  • Yueping Jin
    Department of Gastroenterology, The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, China.
  • Biao Song
    Inner Mongolia Wesure Date Technology Co., Ltd, Inner Mongolia, P.R. China.
  • Qin Sun
    Fred Hutchinson Cancer Research Center, Seattle, WA.
  • Siyuan Wei
    The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei, China.
  • Jing Wu
    School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, Jiangsu, China.
  • Xuejun Li

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