Machine Learning-derived Multi-omics Prognostic Signature of Pyroptosis-related lncRNA with Regard to ZKSCAN2-DT and Tumor Immune Infiltration in Colorectal Cancer.

Journal: Combinatorial chemistry & high throughput screening
PMID:

Abstract

BACKGROUND: Colorectal cancer (CRC) has become the most prevalent gastrointestinal malignant tumor, ranking third (10.2%) in incidence and second (9.2%) in death among all malignancies globally. The most common histological subtype of CRC is colon adenocarcinoma (COAD), although the cause of CRC remains unknown, as there are no valid biomarkers.

Authors

  • Jiamin Chen
  • Dan Jin
    Brainnetome Center & National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
  • Liming Shao
    Department of Gastroenterology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang Province, China.
  • Lingling Wang
    Department of Neurology, Shanghai Pudong New Area People's Hospital, Shanghai, China.
  • Liuzhi Zhou
    Department of Surgical Oncology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310000, Zhejiang Province, China.
  • Jianting Cai