FABRICATION AND EVALUATION OF SMART NANOCRYSTALS OF ARTEMISININ FOR ANTIMALARIAL AND ANTIBACTERIAL EFFICACY.

Journal: African journal of traditional, complementary, and alternative medicines : AJTCAM
Published Date:

Abstract

BACKGROUND: Nanocrystals have the potential to substantially increase dissolution rate, solubility with subsequent enhanced bioavailability via the oral route of a range of poor water soluble drugs. Regardless of other issues, scale up of the batch size is the main issue associated with bottom up approach.

Authors

  • Syed Muhammad Hassan Shah
    Department of Pharmacy, Sarhad University of Science and Information Technology, Peshawar, Pakistan.
  • Farhat Ullah
    Department of Pharmacy, University of Malakand, Chakdara, Dir Lower, Pakistan.
  • Shahzeb Khan
    Department of Pharmacy, University of Malakand, Chakdara, Dir Lower, Pakistan.
  • Syed Muhammad Mukarram Shah
    Department of Pharmacy, University of Malakand, Chakdara, Dir Lower, Pakistan.
  • Mohamad Isreb
    School of Pharmacy, Institute of Life Sciences Research, University of Bradford, West Yorkshire BD7 1DP, UK.