AIMC Topic: Artemisinins

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QSAR Study of Artemisinin Analogues as Antimalarial Drugs by Neural Network and Replacement Method.

Drug research May 30, 2017
Quantitative structure-activity relationship (QSAR) models were derived for 179 analogues of artemisinin, a potent antimalarial agent. Molecular descriptors derived solely from molecular structure were used to represent molecular structure. Utilizing...
Neural Networks, Computer Models, Molecular Antimalarials Artemisinins Quantitative Structure-Activity Relationship
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FABRICATION AND EVALUATION OF SMART NANOCRYSTALS OF ARTEMISININ FOR ANTIMALARIAL AND ANTIBACTERIAL EFFICACY.

African journal of traditional, complementary, and alternative medicines : AJTCAM Nov 23, 2016
BACKGROUND: Nanocrystals have the potential to substantially increase dissolution rate, solubility with subsequent enhanced bioavailability via the oral route of a range of poor water soluble drugs. Regardless of other issues, scale up of the batch s...
Anti-Bacterial Agents Microbial Sensitivity Tests Nanoparticles Escherichia coli Plasmodium falciparum Drug Evaluation, Preclinical Antimalarials Solubility Drug Stability Drug Compounding Artemisinins Shigella
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[Effect of dihydroartemisinin on multidrug resistance of human oral squamous cell carcinoma cell line KBV200 by regulating ROS-MAPK pathway].

Shanghai kou qiang yi xue = Shanghai journal of stomatology Dec 1, 2019
PURROSE: To investigate the effect of dihydroartemisinin (DHA) on multidrug resistance of human oral squamous cell carcinoma cell line KBV200 and to explore its relationship with ROS-MAPK pathway.
Humans Carcinoma, Squamous Cell Reactive Oxygen Species Mouth Neoplasms Artemisinins Drug Resistance, Multiple
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