Exploring T-cell exhaustion features in Acute myocardial infarction for a Novel Diagnostic model and new therapeutic targets by bio-informatics and machine learning.

Journal: BMC cardiovascular disorders
PMID: 38783198

Abstract

BACKGROUND: T-cell exhaustion (TEX), a condition characterized by impaired T-cell function, has been implicated in numerous pathological conditions, but its role in acute myocardial Infarction (AMI) remains largely unexplored. This research aims to identify and characterize all TEX-related genes for AMI diagnosis.

Authors

  • Nake Jin
    Department of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, State Key Laboratory of Transvascular Implantation Devices, Cardiovascular Key Laboratory of Zhejiang Province, Hangzhou, 310009, Zhejiang, China.
  • Jiacheng Rong
    Department of Cardiology, Ningbo Hangzhou Bay Hospital, Ningbo, 315300, Zhejiang, China.
  • Xudong Chen
  • Lei Huang
    School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu, China.
  • Hong Ma
    College of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou, China.

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