A prospective cohort-based artificial intelligence evaluation system for the protective efficacy and immune response of SARS-CoV-2 inactivated vaccines.

Journal: International immunopharmacology
PMID:

Abstract

BACKGROUND: Novel coronaviruses constitute a significant health threat, prompting the adoption of vaccination as the primary preventive measure. However, current evaluations of immune response and vaccine efficacy are deemed inadequate.

Authors

  • Jin Zhang
    Department of Otolaryngology, The Second People's Hospital of Yibin, Yibin, Sichuan, China.
  • Yuan Meng
    State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, 100084, China.
  • Mei Yang
    Department of Geriatric Cardiology; National Center for Clinical Research of Geriatric Diseases, Xiangya Hospital, Central South University, Changsha 410008, China.
  • Wudi Hao
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
  • Jianhua Liu
    School of Materials Science and Engineering, Ocean University of China, Qingdao 266100, China.
  • Lina Wu
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
  • Xiaojun Yu
    School of Automation, Northwestern Polytechnical University, Xi'an 710129, China.
  • Yue Zhang
    Department of Ophthalmology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
  • Baoxu Lin
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
  • Chonghong Xie
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
  • Lili Ge
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
  • Zhijie Zhang
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
  • Weiwei Tong
    Gennlife (Beijing) Biotechnology Co. Ltd., Haidian, Beijing, China.
  • Qing Chang
    Department of Ultrasound, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
  • Yong Liu
    Department of Critical care medicine, Shenzhen Hospital, Southern Medical University, Guangdong, Shenzhen, China.
  • Yixiao Zhang
    Computational Cognition, Vision, and Learning (CCVL), Johns Hopkins University, Baltimore, MD, USA.
  • Xiaosong Qin
    Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China. Electronic address: qinxs@sj-hospital.org.