AIMC Topic: COVID-19 Vaccines
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Effects of a Theory- and Evidence-Based, Motivational Interviewing-Oriented Artificial Intelligence Digital Assistant on Vaccine Attitudes: A Randomized Controlled Trial.
Journal of medical Internet research
Aug 8, 2025
BACKGROUND: Attitude-targeted interventions are important approaches for promoting vaccination. Educational approaches alone cannot effectively cultivate positive vaccine attitudes. Artificial intelligence (AI)-driven chatbots and motivational interv...
Influencing factors and dynamic changes of COVID-19 vaccine hesitancy in China: From the perspective of machine learning analysis.
Human vaccines & immunotherapeutics
Jul 30, 2025
Exploring the influencing factors of COVID-19 vaccine hesitancy and summarizing countermeasures is of great significance for effectively addressing potential public health crises. Based on survey data from China, we employed a Gradient Boosting Decis...
Ethical Implications of Artificial Intelligence in Vaccine Equity: Protocol for Exploring Vaccine Distribution Planning and Scheduling in Pandemics in Low- and Middle-Income Countries.
JMIR research protocols
Jul 9, 2025
BACKGROUND: The COVID-19 pandemic highlighted significant disparities in vaccine distribution, particularly in low- and middle-income countries (LMICs). Artificial intelligence (AI) has emerged as a potential tool to optimize vaccine distribution pla...
Predicting SARS-CoV-2-specific CD4 and CD8 T-cell responses elicited by inactivated vaccines in healthy adults using machine learning models.
Clinical and experimental medicine
Jul 8, 2025
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlights the importance of monitoring immune responses to guide vaccination strategies. Although neutralizing antibodies (NAbs) have garnered increasing ...
Modifiable risk factors of vaccine hesitancy: insights from a mixed methods multiple population study combining machine learning and thematic analysis during the COVID-19 pandemic.
BMC medicine
Mar 12, 2025
BACKGROUND: Vaccine hesitancy, the delay in acceptance or reluctance to vaccinate, ranks among the top threats to global health. Identifying modifiable factors contributing to vaccine hesitancy is crucial for developing targeted interventions to incr...
Artificial intelligence models predicting abnormal uterine bleeding after COVID-19 vaccination.
Scientific reports
Feb 27, 2025
The rapid deployment of COVID-19 vaccines has necessitated the ongoing surveillance of adverse events, with abnormal uterine bleeding (AUB) emerging as a reported concern in vaccinated females. We aimed to develop a machine learning (ML) model to pre...
Improving entity recognition using ensembles of deep learning and fine-tuned large language models: A case study on adverse event extraction from VAERS and social media.
Journal of biomedical informatics
Feb 7, 2025
OBJECTIVE: Adverse event (AE) extraction following COVID-19 vaccines from text data is crucial for monitoring and analyzing the safety profiles of immunizations, identifying potential risks and ensuring the safe use of these products. Traditional dee...
Humoral and cell-mediated immune responses to COVID-19 vaccines up to 6 months post three-dose primary series in adults with inborn errors of immunity and their breakthrough infections.
Frontiers in immunology
Jan 21, 2025
PURPOSE: Many individuals with inborn errors of immunity (IEIs) have poor humoral immune (HI) vaccine responses. Only a few studies have examined specific cell-mediated immune (CMI) responses to coronavirus disease 2019 (COVID-19) vaccines in this po...
Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery.
Nature communications
Dec 30, 2024
Lipid nanoparticles (LNPs) have proven effective in mRNA delivery, as evidenced by COVID-19 vaccines. Its key ingredient, ionizable lipids, is traditionally optimized by inefficient and costly experimental screening. This study leverages artificial i...
Using machine learning for personalized prediction of longitudinal coronavirus disease 2019 vaccine responses in transplant recipients.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Dec 4, 2024
The coronavirus disease 2019 pandemic has underscored the importance of vaccines, especially for immunocompromised populations like solid organ transplant recipients, who often have weaker immune responses. The purpose of this study was to compare de...
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