Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer.

Journal: Pathology oncology research : POR
PMID: 39835329

Abstract

OBJECTIVES: Spingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circulating S1P and anti-ceramide antibody as biomarkers in non-small cell lung cancer (NSCLC).

Authors

  • Lilla Bűdi
    Department of Pulmonology, Semmelweis University, Budapest, Hungary.
  • Dániel Hammer
    Department of Pulmonology, Semmelweis University, Budapest, Hungary.
  • Rita Varga
    Department of Pulmonology, Semmelweis University, Budapest, Hungary.
  • Veronika Müller
    Department of Pulmonology, Semmelweis University, Budapest, Hungary.
  • Ádám Domonkos Tárnoki
    Medical Imaging Centre, Semmelweis University, Budapest, Hungary.
  • Dávid László Tárnoki
    Medical Imaging Centre, Semmelweis University, Budapest, Hungary.
  • Martina Mészáros
    Department of Pulmonology, Semmelweis University, Budapest, Hungary.
  • András Bikov
    Wythenshawe Hospital, Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom.
  • Péter Horváth
    Department of Pulmonology, Semmelweis University, Budapest, Hungary.

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