A pretreatment multiparametric MRI-based radiomics-clinical machine learning model for predicting radiation-induced temporal lobe injury in patients with nasopharyngeal carcinoma.

Journal: Head & neck
PMID:

Abstract

BACKGROUND: To establish and validate a machine learning model using pretreatment multiparametric magnetic resonance imaging-based radiomics data with clinical data to predict radiation-induced temporal lobe injury (RTLI) in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT).

Authors

  • Li Wang
    College of Marine Electrical Engineering, Dalian Maritime University, Dalian, China.
  • Ting Qiu
    Department of Radiation Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
  • Jiawei Zhou
    State Key Laboratory of Oral Diseases, West China School of Stomatology, West China Hospital of Stomatology, Department of Orthodontics, Sichuan University, People's Republic of China.
  • Yinsu Zhu
    Nanjing Medical University, Nanjing, Jiangsu, China.
  • Baozhou Sun
    Department of Radiation Oncology, Washington University School of Medicine, 4921 Parkview Place, Campus Box 8224, St. Louis, MO, 63110, USA.
  • Guanyu Yang
    Laboratory of Image Science and Technology, School of Computer Science and Engineering, Southeast University, Nanjing, China; Key Laboratory of Computer Network and Information Integration (Southeast University), Ministry of Education, Nanjing, China; Centre de Recherche en Information Biomedicale Sino-Francais (LIA CRIBs), Rennes, France.
  • Shengfu Huang
    Department of Radiation Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.
  • Lirong Wu
    School of Engineering, Westlake University, Hangzhou 310024, China.
  • Xia He
    Department of Radiation Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, China.