Currently used dosage regimens of vancomycin fail to achieve therapeutic levels in approximately 40% of intensive care unit patients.

Journal: Revista Brasileira de terapia intensiva

PMID: 28099635

Abstract

OBJECTIVE:: This study aimed to assess whether currently used dosages of vancomycin for treatment of serious gram-positive bacterial infections in intensive care unit patients provided initial therapeutic vancomycin trough levels and to examine possible factors associated with the presence of adequate initial vancomycin trough levels in these patients.

Authors

Vitor Yuzo Obara

Programa de Pós-Graduação em Ciências da Saúde, Universidade Estadual de Londrina - Londrina (PR), Brasil.
Carolina Petrus Zacas

Universidade Estadual de Londrina - Londrina (PR), Brasil.
Claudia Maria Dantas de Maio Carrilho

Universidade Estadual de Londrina - Londrina (PR), Brasil.
Vinicius Daher Alvares Delfino

Universidade Estadual de Londrina - Londrina (PR), Brasil.

Keywords

Acute Kidney Injury Adult Aged Anti-Bacterial Agents Creatinine Dose-Response Relationship, Drug Drug Monitoring Female Gram-Positive Bacterial Infections Humans Intensive Care Units Male Middle Aged Prospective Studies Vancomycin

External Resources

View on PubMed Access via DOI PubMed (28099635)

Currently used dosage regimens of vancomycin fail to achieve therapeutic levels in approximately 40% of intensive care unit patients.

Abstract

Authors

Keywords

External Resources

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