CT-based deep learning radiomics biomarker for programmed cell death ligand 1 expression in non-small cell lung cancer.

Journal: BMC medical imaging
Published Date: Jul 31, 2024

Abstract

BACKGROUND: Programmed cell death ligand 1 (PD-L1), as a reliable predictive biomarker, plays an important role in guiding immunotherapy of lung cancer. To investigate the value of CT-based deep learning radiomics signature to predict PD-L1 expression in non-small cell lung cancers(NSCLCs).

Authors

  • Ting Xu
    Bioresources Green Transformation Collaborative Innovation Center of Hubei Province, College of Life Sciences, Hubei University, Wuhan 430062, Hubei, China.
  • Xiaowen Liu
    School of Informatics and Computing, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana 46202, United States.
  • Yaxi Chen
    The Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
  • Shuxing Wang
    The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China (S.W., X.L., Y.P., J.G.).
  • Changsi Jiang
    Department of Radiology, Shenzhen People's Hospital, the Second Clinical Medical College of Jinan University, Shenzhen, 518020, China.
  • Jingshan Gong
    Department of Radiology, Shenzhen People's Hospital, the Second Clinical Medical College of Jinan University, Shenzhen, 518020, China. jshgong@sina.com.

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