Development and validation of a machine learning-based F-fluorodeoxyglucose PET/CT radiomics signature for predicting gastric cancer survival.

Journal: Cancer imaging : the official publication of the International Cancer Imaging Society
PMID:

Abstract

BACKGROUND: Survival prognosis of patients with gastric cancer (GC) often influences physicians' choice of their follow-up treatment. This study aimed to develop a positron emission tomography (PET)-based radiomics model combined with clinical tumor-node-metastasis (TNM) staging to predict overall survival (OS) in patients with GC.

Authors

  • Huaiqing Zhi
    Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Yilan Xiang
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Chenbin Chen
    Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Weiteng Zhang
    Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Jie Lin
    Department of Reproductive Medicine, Zigong Hospital of Women and Children Health Care, Zigong, China.
  • Zekan Gao
    Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Qingzheng Shen
    Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. Electronic address: sqz879752@gmail.com.
  • Jiancan Shao
    Department of General Surgery, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Xinxin Yang
    Department of General Surgery, the First Affiliated Hospital of Jiamusi University, Jiamusi 154000, Heilongjiang, China.
  • Yunjun Yang
    Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. yyjunjim@163.com.
  • Xiaodong Chen
  • Jingwei Zheng
    Department of General Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Mingdong Lu
    Department of General Surgery, The Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.
  • Bujian Pan
    Department of Hepatobiliary Surgery, Wenzhou Central Hospital, The Dingli Clinical Institute of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, PR China. Electronic address: panbujian@126.com.
  • Qiantong Dong
    Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, China. Electronic address: dongqt2021@wmu.edu.cn.
  • Xian Shen
    Novartis Pharmaceuticals Corporation, East Hanover, New Jersey.
  • Chunxue Ma
    Department of Gastrointestinal Surgery Nursing Unit, Ward 443, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. mcx207@163.com.