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Radiopharmaceuticals

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Evaluating Automated Tools for Lesion Detection on F Fluoroestradiol PET/CT Images and Assessment of Concordance with Standard-of-Care Imaging in Metastatic Breast Cancer.

Radiology. Imaging cancer
Purpose To evaluate two automated tools for detecting lesions on fluorine 18 (F) fluoroestradiol (FES) PET/CT images and assess concordance of F-FES PET/CT with standard diagnostic CT and/or F fluorodeoxyglucose (FDG) PET/CT in patients with breast c...

Enhancing F-FDG PET image quality and lesion diagnostic performance across different body mass index using the deep progressive learning reconstruction algorithm.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: As body mass index (BMI) increases, the quality of 2-deoxy-2-[fluorine-18]fluoro-D-glucose (F-FDG) positron emission tomography (PET) images reconstructed with ordered subset expectation maximization (OSEM) declines, negatively impacting ...

Identification of HER2-over-expression, HER2-low-expression, and HER2-zero-expression statuses in breast cancer based on F-FDG PET/CT radiomics.

Cancer imaging : the official publication of the International Cancer Imaging Society
PURPOSE: According to the updated classification system, human epidermal growth factor receptor 2 (HER2) expression statuses are divided into the following three groups: HER2-over-expression, HER2-low-expression, and HER2-zero-expression. HER2-negati...

Artificial intelligence algorithm for preoperative prediction of FIGO stage in ovarian cancer based on clinical features integrated 18F-FDG PET/CT metabolic and radiomics features.

Journal of cancer research and clinical oncology
PURPOSE: The International Federation of Gynecology and Obstetric (FIGO) stage is critical to guiding the treatments of ovarian cancer (OC). We tried to develop a model to predict the FIGO stage of OC through machine learning algorithms with patients...

Machine learning models for enhanced diagnosis and risk assessment of prostate cancer with Ga-PSMA-617 PET/CT.

European journal of radiology
OBJECTIVE: Prostate cancer (PCa) is highly heterogeneous, making early detection of adverse pathological features crucial for improving patient outcomes. This study aims to predict PCa aggressiveness and identify radiomic and protein biomarkers assoc...

F-FDG PET/CT-based deep learning models and a clinical-metabolic nomogram for predicting high-grade patterns in lung adenocarcinoma.

BMC medical imaging
BACKGROUND: To develop and validate deep learning (DL) and traditional clinical-metabolic (CM) models based on 18 F-FDG PET/CT images for noninvasively predicting high-grade patterns (HGPs) of invasive lung adenocarcinoma (LUAD).

Machine learning algorithms integrating positron emission tomography/computed tomography features to predict pathological complete response after neoadjuvant chemoimmunotherapy in lung cancer.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
OBJECTIVES: Reliable methods for predicting pathological complete response (pCR) in non-small cell lung cancer (NSCLC) patients undergoing neoadjuvant chemoimmunotherapy are still under exploration. Although Fluorine-18 fluorodeoxyglucose-positron em...

Characterization of Effective Half-Life for Instant Single-Time-Point Dosimetry Using Machine Learning.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Single-time-point (STP) image-based dosimetry offers a more convenient approach for clinical practice in radiopharmaceutical therapy (RPT) compared with conventional multiple-time-point image-based dosimetry. Despite numerous advancements, current ST...