AIMC Topic: Radiopharmaceuticals

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Experimental approach for optimizing dose regimen of 68Ga-DOTATATE PET/CT for neuroendocrine tumor (NET) imaging in current high sensitivity scanners: Phantom and Patient Study.

Nuklearmedizin. Nuclear medicine
This study aimed to determine the optimized scan time and injected activity regimen for clinical Ga DOTATATE PET/CT in neuroendocrine tumor imaging through an experimental approach without using machine learning techniques.A NEMA PET body phantom was...

Prognostic Value of AI-Assisted Lesion Tracking on End-of-Treatment PSMA PET in mCRPC Patients Treated with Lu-PSMA: A Retrospective, Single-Center Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
This study aimed to explore the prognostic value of the artificial intelligence-assisted lesion tracking applied to prostate-specific membrane antigen (PSMA) PET in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with PS...

Local large arterial perivascular adipose tissue metabolic and anatomical features are associated with hypertensive clinical outcomes: a PET/CT-based study.

Annals of medicine
OBJECTIVE: This study investigated the relationship between anatomical and metabolic characteristics of large arterial perivascular adipose tissue (PVAT) and hypertensive clinical outcomes using positron emission tomography-computed tomography (PET/C...

Comparative Diagnostic Accuracy of AI-Assisted Fluorine-18 Fluorodeoxyglucose Positron Emission Tomography Versus Structural Magnetic Resonance Imaging in Alzheimer Disease: Systematic Review and Meta-Analysis.

JMIR aging
BACKGROUND: Neuroimaging is crucial in the diagnosis of Alzheimer disease (AD). In recent years, artificial intelligence (AI)-based neuroimaging technology has rapidly developed, providing new methods for accurate diagnosis of AD, but its performance...

A proof of concept study of F-FDG PET/CT patient-level radiomics identify refractory/relapsed diffuse large B-cell lymphoma.

Scientific reports
This study aimed to evaluate diffuse large B-cell lymphoma (DLBCL) patients who have refractory/relapsed disease and characterize the heterogeneity of DLBCL using patient-level radiomics analysis based on F-FDG PET/CT. A total of 132 patients diagnos...

External validation of deep learning-derived 18F-FDG PET/CT delta biomarkers for loco-regional control in head and neck cancer.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Delta biomarkers that reflect changes in tumour burden over time can support personalised follow-up in head and neck cancer. However, their clinical use can be limited by the need for manual image segmentation. This study exte...

Machine Learning-Driven radiomics on 18 F-FDG PET for glioma diagnosis: a systematic review and meta-analysis.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Machine learning (ML) applied to radiomics has revolutionized neuro-oncological imaging, yet the diagnostic performance of ML models based specifically on ^18F-FDG PET features in glioma remains poorly characterized.

Multimodal imaging deep learning model for predicting extraprostatic extension in prostate cancer using MpMRI and 18 F-PSMA-PET/CT.

Cancer imaging : the official publication of the International Cancer Imaging Society
OBJECTIVE: This study aimed to construct a multimodal imaging deep learning (DL) model integrating mpMRI and F-PSMA-PET/CT for the prediction of extraprostatic extension (EPE) in prostate cancer, and to assess its effectiveness in enhancing the diagn...

18F-FDG PET/CT-based deep radiomic models for enhancing chemotherapy response prediction in breast cancer.

Medical oncology (Northwood, London, England)
Enhancing the accuracy of tumor response predictions enables the development of tailored therapeutic strategies for patients with breast cancer. In this study, we developed deep radiomic models to enhance the prediction of chemotherapy response after...

An interpretable machine learning model for predicting bone marrow invasion in patients with lymphoma via F-FDG PET/CT: a multicenter study.

BMC medical informatics and decision making
PURPOSE: Accurate identification of bone marrow invasion (BMI) is critical for determining the prognosis of and treatment strategies for lymphoma. Although bone marrow biopsy (BMB) is the current gold standard, its invasive nature and sampling errors...