Screening of Secretory Proteins Linking Major Depressive Disorder with Heart Failure Based on Comprehensive Bioinformatics Analysis and Machine Learning.

Journal: Biomolecules
PMID:

Abstract

BACKGROUND: Major depressive disorder (MDD) plays a crucial role in the occurrence of heart failure (HF). This investigation was undertaken to explore the possible mechanism of MDD's involvement in HF pathogenesis and identify candidate biomarkers for the diagnosis of MDD with HF.

Authors

  • Chuanjing Zhang
    Ningbo University Health Science Center, Ningbo 315040, China.
  • Yongfei Song
    Ningbo University Health Science Center, Ningbo 315040, China.
  • Lichao Cen
    Ningbo University Health Science Center, Ningbo 315040, China.
  • Chen Huang
    Department of Pharmacy, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
  • Jianqing Zhou
    Ningbo University Health Science Center, Ningbo 315040, China.
  • Jiangfang Lian
    Ningbo University Health Science Center, Ningbo 315040, China.