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Japanese journal of infectious diseases

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Prediction of Contact Residues in Anti-HIV Neutralizing Antibody by Deep Learning.

Japanese journal of infectious diseases Jan 31, 2020
The monoclonal antibody 1C10 targets the V3 loop of HIV-1 and neutralizes a broad range of clade B viruses. However, the mode of interaction between 1C10 and the V3 loop remains unclear because crystallization of 1C10 and the V3 peptide was unsuccess...
Humans Molecular Docking Simulation Deep Learning Antibodies, Monoclonal Peptide Fragments Antibodies, Neutralizing Amino Acid Sequence Amino Acid Substitution HIV Antibodies HIV Envelope Protein gp120 Binding Sites, Antibody
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Data Mining and Machine Learning Algorithms Using IL28B Genotype and Biochemical Markers Best Predicted Advanced Liver Fibrosis in Chronic Hepatitis C.

Japanese journal of infectious diseases Dec 26, 2017
IL28B single nucleotide polymorphism (rs12979860) is an etiology-independent predictor of hepatitis C virus (HCV)-related hepatic fibrosis. Data mining is a method of predictive analysis which can explore tremendous volumes of information from health...
Humans Machine Learning Algorithms Retrospective Studies Female Male Middle Aged Genetic Predisposition to Disease Polymorphism, Single Nucleotide Liver Cirrhosis Interleukins Genetic Markers Data Mining Hepatitis C, Chronic Interferons
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