AIMC Topic: Hepatitis C, Chronic

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Direct-acting antivirals (DAA) positively affect depression and cognitive function in patients with chronic hepatitis C.

PloS one Apr 4, 2025
The aim of the study was to determine how depression and cognitive dysfunction in patients with chronic hepatitis C virus (HCV) infection are affected by treatment with direct-acting antivirals (DAA). Fifty-two chronic hepatitis C patients underwent ...
Humans Female Middle Aged Aged Depression Antiviral Agents Adult Cognition Male Hepatitis C, Chronic Neuropsychological Tests
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Fibrosis and inflammatory activity diagnosis of chronic hepatitis C based on extreme learning machine.

Scientific reports Jan 2, 2025
The traditional diagnosis of chronic hepatitis C usually relies on liver biopsy. Diagnosing chronic hepatitis C based on serum indices provides a non-invasive way to determine the stage of chronic hepatitis C without liver biopsy. In this paper, we p...
Female Male Inflammation Liver Cirrhosis Cluster Analysis Hepatitis C, Chronic Humans Machine Learning Biomarkers
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AI-Safe-C score: Assessing liver-related event risks in patients without cirrhosis after successful direct-acting antiviral treatment.

Journal of hepatology Sep 20, 2024
BACKGROUND & AIMS: Direct-acting antivirals (DAAs) have considerably improved chronic hepatitis C (HCV) treatment; however, follow-up after sustained virological response (SVR) typically neglects the risk of liver-related events (LREs). This study in...
ROC Curve Liver Neoplasms Antiviral Agents Liver Cirrhosis Hepatitis C, Chronic France Aged Humans Adult Artificial Intelligence Male Hong Kong Republic of Korea Middle Aged Sustained Virologic Response Female Risk Assessment Risk Factors
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Artificial intelligence-assisted identification and retrieval of chronic hepatitis C patients lost to follow-up in the health area of Pontevedra and O Salnés (Spain).

Gastroenterologia y hepatologia Jun 29, 2024
OBJECTIVE: Direct-acting antivirals (DAAs) to treat hepatitis C virus (HCV) infection offer an opportunity to eliminate the disease. This study aimed to identify and relink to care HCV patients previously lost to medical follow-up in the health area ...
Middle Aged Antiviral Agents Liver Cirrhosis Hepatitis C, Chronic Lost to Follow-Up Spain Humans Retrospective Studies Artificial Intelligence Female Aged Adult Male
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Hepatitis C viral load and genotypes among Nigerian subjects with chronic infection and implication for patient management: a retrospective review of data.

The Pan African medical journal Dec 10, 2020
INTRODUCTION: Hepatitis C Virus (HCV) is highly infectious with no currently available vaccine. Prior to treatment, it is recommended to confirm HCV infection with either quantitative or qualitative nucleic acid test. Access to these assays in Nigeri...
Hepacivirus Adolescent Young Adult Humans Nigeria Adult Retrospective Studies Hepatitis C, Chronic Viral Load Male Female Antiviral Agents Middle Aged Aged Genotype Prevalence Aged, 80 and over
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Assessment of a Deep Learning Model to Predict Hepatocellular Carcinoma in Patients With Hepatitis C Cirrhosis.

JAMA network open Sep 1, 2020
IMPORTANCE: Deep learning, a family of machine learning models that use artificial neural networks, has achieved great success at predicting outcomes in nonmedical domains.
Humans Neural Networks, Computer Prognosis Electronic Health Records Incidence Liver Neoplasms Carcinoma, Hepatocellular Liver Cirrhosis Area Under Curve Hepatitis C, Chronic Female Male Middle Aged Risk Assessment Deep Learning Sustained Virologic Response Veterans Health Services Chronic Disease Indicators
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Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Jan 29, 2019
BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screening for esophageal varices (EVs) are found to have no or only small EVs. Endoscopic screening for EVs is therefore a potentially deferrable procedure t...
Aspartate Aminotransferases Bilirubin Liver Cirrhosis, Alcoholic Gastrointestinal Hemorrhage Hepatic Encephalopathy Humans Hemoglobins Serum Albumin Machine Learning Sodium Blood Urea Nitrogen Prospective Studies International Normalized Ratio Platelet Count Endoscopy, Digestive System Female Esophageal and Gastric Varices Hepatitis C, Chronic Male Aged Thrombocytopenia Ascites Alanine Transaminase Middle Aged Creatinine Risk Assessment Non-alcoholic Fatty Liver Disease Severity of Illness Index Liver Cirrhosis Mass Screening
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Machine learning models to predict disease progression among veterans with hepatitis C virus.

PloS one Jan 4, 2019
BACKGROUND: Machine learning (ML) algorithms provide effective ways to build prediction models using longitudinal information given their capacity to incorporate numerous predictor variables without compromising the accuracy of the risk prediction. C...
Proportional Hazards Models Veterans Male Middle Aged Disease Progression Models, Theoretical Hepatitis C, Chronic Humans Machine Learning
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Ritonavir-boosted paritaprevir, ombitasvir plus ribavirin could improve eGFR in patients with renal impairment and HCV: an Egyptian cohort.

Expert review of gastroenterology & hepatology Nov 13, 2018
BACKGROUND: The present study aimed at evaluation of changes in estimated glomerular filtration rate (eGFR) among chronic Hepatitis C virus (HCV) patients with chronic kidney disease (CKD) Stages 3-5 who were treated with 12 weeks of ritonavir-booste...
Humans Prospective Studies Female Aged Young Adult Viral Load Sustained Virologic Response Sulfonamides Adult Time Factors Hepacivirus Male Antiviral Agents Anilides Proline Middle Aged Treatment Outcome Genotype Carbamates Drug Therapy, Combination Renal Dialysis Glomerular Filtration Rate Hepatitis C, Chronic Kidney Lactams, Macrocyclic Cyclopropanes Valine Renal Insufficiency, Chronic Macrocyclic Compounds Recovery of Function Ribavirin Egypt
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Data Mining and Machine Learning Algorithms Using IL28B Genotype and Biochemical Markers Best Predicted Advanced Liver Fibrosis in Chronic Hepatitis C.

Japanese journal of infectious diseases Dec 26, 2017
IL28B single nucleotide polymorphism (rs12979860) is an etiology-independent predictor of hepatitis C virus (HCV)-related hepatic fibrosis. Data mining is a method of predictive analysis which can explore tremendous volumes of information from health...
Female Male Middle Aged Genetic Predisposition to Disease Polymorphism, Single Nucleotide Liver Cirrhosis Interleukins Genetic Markers Data Mining Hepatitis C, Chronic Interferons Humans Machine Learning Algorithms Retrospective Studies
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