AIMC Topic: Bone Morphogenetic Protein Receptors

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Machine learning-guided evolution of BMP-2 knuckle Epitope-Derived osteogenic peptides to target BMP receptor II.

Journal of drug targeting May 1, 2020
Bone morphogenetic protein-2 (BMP-2) is a key regulator of bone formation, growth and regeneration, which contains a conformational wrist epitope and a linear knuckle epitope that are functionally responsible for the protein by mediating its interact...
Humans Machine Learning Animals Peptides Mice Epitopes Osteogenesis Crystallization Bone Morphogenetic Protein Receptors
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Effect of bone morphogenetic proteins 2 and 4 on survival and development of bovine secondary follicles cultured in vitro.

Theriogenology Dec 27, 2017
This study evaluated the effect of bone morphogenetic proteins 2 (BMP2) and 4 (BMP2) on follicle development and mRNA expression for GDF9, Cyclin B1, BMPR1A, BMPR1B, BMPRII, FSHR and SMAD1 in bovine secondary follicles cultured in vitro. Isolated sec...
Cells, Cultured Female Animals Cattle Cell Survival Oocytes Gene Expression Regulation Ovarian Follicle Bone Morphogenetic Protein 2 Bone Morphogenetic Protein 4 Bone Morphogenetic Protein Receptors Oogenesis
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