AIMC Topic: BRCA1 Protein

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Molecular and epigenetic profiles of BRCA1-like hormone-receptor-positive breast tumors identified with development and application of a copy-number-based classifier.

Breast cancer research : BCR Jan 25, 2019
BACKGROUND: BRCA1-mutated cancers exhibit deficient homologous recombination (HR) DNA repair, resulting in extensive copy number alterations and genome instability. HR deficiency can also arise in tumors without a BRCA1 mutation. Compared with other ...
Humans Female Aged Adult Breast Neoplasms Middle Aged Epigenomics Support Vector Machine DNA Methylation DNA Copy Number Variations Breast Survival Analysis Datasets as Topic CpG Islands Promoter Regions, Genetic Receptors, Estrogen Receptors, Progesterone BRCA1 Protein Homologous Recombination
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