AIMC Topic: Carcinoma, Hepatocellular

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Regulation of demethylation and re-expression of RASSF1A gene in hepatocellular carcinoma cell lines treated with NCTD in vitro.

Journal of cancer research and therapeutics Jan 1, 2015
BACKGROUND: Hepatocellular carcinoma, a lethal malignant neoplasm with poor prognosis, has dismal results of surgical resection and chemoradiotherapy. Norcantharidin (NCTD), the demethylated analog of cantharidin derived from a traditional Chinese me...
Humans In Vitro Techniques Liver Neoplasms Carcinoma, Hepatocellular Gene Expression Regulation, Neoplastic DNA Methylation Blotting, Western Tumor Suppressor Proteins Bridged Bicyclo Compounds, Heterocyclic Tumor Cells, Cultured
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Identification of hepatocellular carcinoma-related genes with a machine learning and network analysis.

Journal of computational biology : a journal of computational molecular cell biology Jan 1, 2015
Liver cancer is one of the leading causes of cancer mortality worldwide. Hepatocellular carcinoma (HCC) is the main type of liver cancer. We applied a machine learning approach with maximum-relevance-minimum-redundancy (mRMR) algorithm followed by in...
Humans Artificial Intelligence Liver Neoplasms Carcinoma, Hepatocellular Gene Regulatory Networks Models, Genetic Databases, Genetic Gene Ontology Genes, Neoplasm
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