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In Vitro Techniques

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The Effect of Different Bleaching Techniques Using 6% Hydrogen Peroxide: Penetration Inside the Pulp Cavity, Bleaching Efficacy and Toxicity.

Brazilian dental journal
This in vitro study aimed to quantify the penetration of hydrogen peroxide (HP), bleaching efficacy (BE) and toxicity in larvae in different bleaching techniques using 6% HP. Sixty maxillary premolars were divided in six groups (n = 10): Pola Luminat...

Impact of dental pulp cells-derived small extracellular vesicles on the properties and behavior of dental pulp cells: an in-vitro study.

BMC oral health
BACKGROUND: Dental pulp cells-derived small extracellular vesicles (DPCs-sEVs) had shown immunomodulatory, anti-inflammatory, and tissue function restorative abilities. Therefore, DPCs-sEVs should be considered as a promising regenerative tool for de...

Cervical wear pathobiology by robot-simulated 3-year toothbrushing - New methodological approach.

Archives of oral biology
OBJECTIVES: An ex-vivo study was aimed at (i) programming clinically validated robot three-year random toothbrushing, (ii) evaluating cervical macro- and microwear patterns on all tooth groups of different functional age, (iii) documenting and codifi...

Comparison of the Efficacy of Artificial Intelligence-Powered Software in Crown Design: An In Vitro Study.

International dental journal
INTRODUCTION AND AIMS: Artificial intelligence (AI) has been adopted in the field of dental restoration. This study aimed to evaluate the time efficiency and morphological accuracy of crowns designed by two AI-powered software programs in comparison ...

In vitro metabolic studies and machine learning analysis of mass spectrometry data: A dual strategy for differentiating alpha-pyrrolidinohexiophenone (α-PHP) and alpha-pyrrolidinoisohexanophenone (α-PiHP) in urine analysis.

Forensic science international
Synthetic cathinones are some of the most prevalent new psychoactive substances (NPSs) globally, with alpha-pyrrolidinoisohexanophenone (α-PiHP) being particularly noted for its widespread use in the United States, Europe, and Taiwan. However, the an...

A transcrestal sinus floor elevation strategy based on a haptic robot system: An in vitro study.

Clinical implant dentistry and related research
OBJECTIVES: To reveal the force profiles recorded by haptic autonomous robotic force feedback during the transcrestal sinus floor elevation (TSFE) process, providing a reference for the surgery strategy during TSFE.

Accuracy of Zygomatic Implant Placement Using Task-Autonomous Robotic System or Dynamic Navigation: An In Vitro Study.

Clinical oral implants research
OBJECTIVES: To evaluate and compare the accuracy of task-autonomous robot-assisted implant surgery (RAIS) and dynamic computer-assisted implant surgery (dCAIS) for zygomatic implant placement.

Quantitative in-vitro assessment of a novel robot-assisted system for cochlear implant electrode insertion.

International journal of computer assisted radiology and surgery
PURPOSE: As an increasing number of cochlear implant candidates exhibit residual inner ear function, hearing preservation strategies during implant insertion are gaining importance. Manual implantation is known to induce traumatic force and pressure ...

The role of artificial intelligence in intraoral scanning for complete-arch digital impressions: An in vitro study.

Journal of dentistry
OBJECTIVES: Artificial intelligence (AI) is increasingly being integrated into intraoral scanners (IOS) to improve the quality of digital impressions. However, information on the accuracy of AI-assisted virtual models is limited. This study aimed to ...

Interpretable machine learning unveils key predictors and default values in an expanded database of human in vitro dermal absorption studies with pesticides.

Regulatory toxicology and pharmacology : RTP
The skin is the main route of exposure to plant protection products for operators, workers, residents, and bystanders. Assessing dermal absorption is key for evaluating pesticide exposure. The initial approach to risk assessment involves using defaul...