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Cell Movement

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Paeonol impacts ovarian cancer cell proliferation, migration, invasion and apoptosis via modulating the transforming growth factor beta/smad3 signaling pathway.

Journal of physiology and pharmacology : an official journal of the Polish Physiological Society
Paeonol (2-hydroxy-4-methoxyphenylacetophenone) is a natural phenolic component isolated from the root bark of peony with multiple pharmacological activities and has been proven to have anti-cancer effects. The objective of this study is to investiga...

Effects of grape juice intake on the cell migration properties in overweight women: Modulation mechanisms of cell migration in vitro by delphinidin-3-O-glucoside.

Food research international (Ottawa, Ont.)
Overweight and obesity are typical conditions of chronic low-intensity systemic inflammatory responses, and both have become more common in recent decades, which emphasizes the necessity for healthier diet intake. Fruits such as grapes are rich in an...

The effect of thalidomide on the invasive ability of gastric cancer cells by regulating miR-524-5p/FSTL1.

Cellular and molecular biology (Noisy-le-Grand, France)
This study aimed to investigate the effect of thalidomide (Thal) regulating microRNA (miR)-524-5p/follistatin-like protein 1 (FSTL1) on the invasion ability of gastric cancer cells. For this purpose, real-time fluorescent quantitative PCR (RT-qPCR) w...

Machine learning approaches for predicting Cracking Tolerance Index (CTIndex) of asphalt concrete containing reclaimed asphalt pavement.

PloS one
One of the various sorts of damage to asphalt concrete is cracking. Repeated loads, the deterioration or aging of material combinations, or structural factors can contribute to the development of cracks. Asphalt concrete's crack resistance is represe...

COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning.

Communications biology
Cells are the singular building blocks of life, and a comprehensive understanding of morphology, among other properties, is crucial to the assessment of underlying heterogeneity. We developed Computational Sorting and Mapping of Single Cells (COSMOS)...

Applying artificial intelligence to determination of legal age of majority from radiographic data.

Morphologie : bulletin de l'Association des anatomistes
Forensic odontologists use biological patterns to estimate chronological age for the judicial system. The age of majority is a legally significant period with a limited set of reliable oral landmarks. Currently, experts rely on the questionable devel...

scNAT: a deep learning method for integrating paired single-cell RNA and T cell receptor sequencing profiles.

Genome biology
Many deep learning-based methods have been proposed to handle complex single-cell data. Deep learning approaches may also prove useful to jointly analyze single-cell RNA sequencing (scRNA-seq) and single-cell T cell receptor sequencing (scTCR-seq) da...

Rapid dataset generation methods for stacked construction solid waste based on machine vision and deep learning.

PloS one
The development of urbanization has brought convenience to people, but it has also brought a lot of harmful construction solid waste. The machine vision detection algorithm is the crucial technology for finely sorting solid waste, which is faster and...

Eravacycline, an antibacterial drug, repurposed for pancreatic cancer therapy: insights from a molecular-based deep learning model.

Briefings in bioinformatics
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) remains a serious threat to health, with limited effective therapeutic options, especially due to advanced stage at diagnosis and its inherent resistance to chemotherapy, making it one of the leadin...

Identification of BGN positive fibroblasts as a driving factor for colorectal cancer and development of its related prognostic model combined with machine learning.

BMC cancer
BACKGROUND: Numerous studies have indicated that cancer-associated fibroblasts (CAFs) play a crucial role in the progression of colorectal cancer (CRC). However, there are still many unknowns regarding the exact role of CAF subtypes in CRC.