AIMC Topic: Channelrhodopsins
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Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics.
Nature methods
Oct 14, 2019
We engineered light-gated channelrhodopsins (ChRs) whose current strength and light sensitivity enable minimally invasive neuronal circuit interrogation. Current ChR tools applied to the mammalian brain require intracranial surgery for transgene deli...
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