AIMC Topic: Computer Simulation

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A Machine Learning Algorithm to Predict the Starting Dose of Daptomycin.

Clinical pharmacokinetics Jul 31, 2024
BACKGROUND AND OBJECTIVE: The dosage of daptomycin is usually based on body weight. However, it has been shown that this approach yields too high an exposure in obese patients. Pharmacokinetic and pharmacodynamic indexes (PK/PD) have been proposed fo...
Computer Simulation Female Adult Male Aged Machine Learning Algorithms Anti-Bacterial Agents Humans Daptomycin Monte Carlo Method Middle Aged Dose-Response Relationship, Drug Models, Biological Body Weight Area Under Curve
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Neural waves and computation in a neural net model II: Data-like structures and the dynamics of episodic memory.

Journal of computational neuroscience Jul 31, 2024
The computational resources of a neuromorphic network model introduced earlier were investigated in the first paper of this series. It was argued that a form of ubiquitous spontaneous local convolution enabled logical gate-like neural motifs to form ...
Models, Neurological Neurons Nonlinear Dynamics Computer Simulation Animals Nerve Net Memory, Episodic Humans Neural Networks, Computer
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Multitask learning of a biophysically-detailed neuron model.

PLoS computational biology Jul 31, 2024
The human brain operates at multiple levels, from molecules to circuits, and understanding these complex processes requires integrated research efforts. Simulating biophysically-detailed neuron models is a computationally expensive but effective meth...
Neurons Magnetoencephalography Membrane Potentials Models, Neurological Computer Simulation Action Potentials Electroencephalography Computational Biology Humans Machine Learning Brain Neural Networks, Computer
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Improved fixed-time stability analysis and applications to synchronization of discontinuous complex-valued fuzzy cellular neural networks.

Neural networks : the official journal of the International Neural Network Society Jul 30, 2024
This article mainly centers on proposing new fixed-time (FXT) stability lemmas of discontinuous systems, in which novel optimization approaches are utilized and more relaxed conditions are required. The conventional discussions about Vt>1 and 0
Fuzzy Logic Neural Networks, Computer Computer Simulation Algorithms Time Factors
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Deep Learning-Based Techniques in Glioma Brain Tumor Segmentation Using Multi-Parametric MRI: A Review on Clinical Applications and Future Outlooks.

Journal of magnetic resonance imaging : JMRI Jul 29, 2024
This comprehensive review explores the role of deep learning (DL) in glioma segmentation using multiparametric magnetic resonance imaging (MRI) data. The study surveys advanced techniques such as multiparametric MRI for capturing the complex nature o...
Humans Neural Networks, Computer Computer Simulation Data Accuracy Deep Learning Image Interpretation, Computer-Assisted Brain Neoplasms Image Processing, Computer-Assisted Multiparametric Magnetic Resonance Imaging Disease Progression Glioma
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Detecting differentially expressed genes from RNA-seq data using fuzzy clustering.

The international journal of biostatistics Jul 29, 2024
A two-group comparison test is generally performed on RNA sequencing data to detect differentially expressed genes (DEGs). However, the accuracy of this method is low due to the small sample size. To address this, we propose a method using fuzzy clus...
Sequence Analysis, RNA Fuzzy Logic Cluster Analysis Gene Expression Profiling RNA-Seq Sample Size Humans Computer Simulation
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Prescribed performance adaptive neural event-triggered control for switched nonlinear cyber-physical systems under deception attacks.

Neural networks : the official journal of the International Neural Network Society Jul 27, 2024
In this paper, the design of an adaptive neural event-triggered control scheme for a class of switched nonlinear systems affected by external disturbances and deception attacks is presented. In order to address the effects caused by unknown disturban...
Algorithms Computer Simulation Deception Nonlinear Dynamics Neural Networks, Computer Computer Security
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A Hyper-Transformer model for Controllable Pareto Front Learning with Split Feasibility Constraints.

Neural networks : the official journal of the International Neural Network Society Jul 26, 2024
Controllable Pareto front learning (CPFL) approximates the Pareto optimal solution set and then locates a non-dominated point with respect to a given reference vector. However, decision-maker objectives were limited to a constraint region in practice...
Feasibility Studies Algorithms Humans Computer Simulation Neural Networks, Computer Deep Learning
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Optimal synchronization with L-gain performance: An adaptive dynamic programming approach.

Neural networks : the official journal of the International Neural Network Society Jul 25, 2024
This paper studies an optimal synchronous control protocol design for nonlinear multi-agent systems under partially known dynamics and uncertain external disturbance. Under some mild assumptions, Hamilton-Jacobi-Isaacs equation is derived by the perf...
Nonlinear Dynamics Neural Networks, Computer Algorithms Computer Simulation
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Advancements in nanobody generation: Integrating conventional, in silico, and machine learning approaches.

Biotechnology and bioengineering Jul 25, 2024
Nanobodies, derived from camelids and sharks, offer compact, single-variable heavy-chain antibodies with diverse biomedical potential. This review explores their generation methods, including display techniques on phages, yeast, or bacteria, and comp...
Computer Simulation Animals Humans Single-Domain Antibodies Machine Learning
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