AIMC Topic: Crizotinib
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Explainable artificial intelligence for precision medicine in acute myeloid leukemia.
Frontiers in immunology
Sep 29, 2022
Artificial intelligence (AI) can unveil novel personalized treatments based on drug screening and whole-exome sequencing experiments (WES). However, the concept of "black box" in AI limits the potential of this approach to be translated into the clin...
Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects.
Nature communications
Dec 1, 2020
We present comboFM, a machine learning framework for predicting the responses of drug combinations in pre-clinical studies, such as those based on cell lines or patient-derived cells. comboFM models the cell context-specific drug interactions through...
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