AIMC Topic: Lymphoma

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Automated Classification of Lymphoma Subtypes From Histopathological Images Using a U-Net Deep Learning Model: Comparative Evaluation Study.

JMIR medical informatics
BACKGROUND: Accurate classification and grading of lymphoma subtypes are essential for treatment planning. Traditional diagnostic methods face challenges of subjectivity and inefficiency, highlighting the need for automated solutions based on deep le...

Exploring DNA methylation profiles in blood samples of canine gastrointestinal lymphoma.

PloS one
Blood-based testing represents a valuable tool for the detection and monitoring of patient conditions in both human and veterinary medicine. When conventional tissue-based diagnosis is challenging, blood-derived measurements allow for minimally invas...

Normal twin PET: personalized generative modeling for confounder correction and anomaly detection in whole-body PET/CT.

Scientific reports
Variable physiological [F]FDG uptake patterns and a lack of labelled data make it challenging to automatically distinguish normal from pathological suspicious uptake in whole-body PET/CT imaging. We propose a deep learning method that generates patie...

A noninvasive machine learning model using a complete blood count for screening of primary vitreoretinal lymphoma.

Nature communications
Primary vitreoretinal lymphoma (PVRL) is a rare and aggressive intraocular malignancy that is frequently misdiagnosed because of its nonspecific early manifestations and the lack of effective screening tools. We conduct a multicentre case-control stu...

Online Health-Seeking Behaviors and Information Needs Among Patients With Lymphoma in China: Study of Regional and Temporal Trends.

Journal of medical Internet research
BACKGROUND: Health disparities are closely associated with socioeconomic inequalities. Although this relationship is well recognized in the context of traditional health care access, its influence on online health-seeking behaviors such as posting qu...

Interpretable radiomics-based machine learning model for differentiating glioblastoma from primary central nervous system lymphoma using contrast-enhanced T1-weighted imaging.

Scientific reports
This study aimed to develop and validate an interpretable radiomics-based machine learning model using contrast-enhanced T1-weighted imaging (CE-T1WI) to differentiate glioblastoma (GB) from primary central nervous system lymphoma (PCNSL), while comp...

Enhancing lymphoma cancer detection using deep transfer learning on histopathological images.

Scientific reports
Lymphoma histopathological diagnosis is complex due to rare subtypes, morphological overlaps, and poor tumor differentiation. In this paper, an AI-based system using deep transfer learning and simulated federated learning is developed to classify two...

Clinical Information Extraction From Notes of Veterans With Lymphoid Malignancies: Natural Language Processing Study.

JMIR medical informatics
BACKGROUND: Clinical natural language processing (cNLP) techniques are commonly developed and used to extract information from clinical notes to facilitate clinical decision-making and research. However, they are less established for rare diseases su...

Predicting in-hospital mortality in ICU patients with lymphoma using machine learning models.

PloS one
BACKGROUND: Lymphoma is a severe condition with high mortality rates, often requiring ICU admission. Traditional risk stratification tools like SOFA and APACHE scores struggle to capture complex clinical interactions. Machine learning (ML) models off...

Serum metabolic patterns reveal the diagnostic and prognostic role of alanine abnormality in ocular adnexal lymphoma.

Proceedings of the National Academy of Sciences of the United States of America
Ocular adnexal lymphoma (OAL) is the most common orbital malignancy in adults. Advanced tools for precise diagnosis and prognosis of OAL are in demand. Here, the nanoparticle-enhanced laser desorption/ionization mass spectrometry was applied for the ...