AIMC Topic: Dihydropteroate Synthase

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Dihydropteroate synthase based sensor for screening multi-sulfonamides residue and its comparison with broad-specific antibody based immunoassay by molecular modeling analysis.

Analytica chimica acta Nov 8, 2018
A biosensor that could simultaneously detect multi-analyte as many as in a single test is more favored when facing lots of samples for screening purpose. In such a biosensor, the recognition element with broad specificity and highly affinity is a key...
Animals Biosensing Techniques Antibodies, Monoclonal Models, Molecular Immunoassay Sulfonamides Milk Dihydropteroate Synthase
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Design, synthesis, antibacterial evaluation and molecular docking studies of some new quinoxaline derivatives targeting dihyropteroate synthase enzyme.

Bioorganic chemistry Dec 5, 2017
Development of new antimicrobial agents is a good solution to overcome drug-resistance problems. From this perspective, new quinoxaline derivatives bearing various bioactive heterocyclic moieties (thiadiazoles, oxadiazoles, pyrazoles and thiazoles) w...
Anti-Bacterial Agents Molecular Docking Simulation Drug Design Microbial Sensitivity Tests Protein Binding Structure-Activity Relationship Molecular Structure Hydrophobic and Hydrophilic Interactions Catalytic Domain Gram-Negative Bacteria Gram-Positive Bacteria Hydrogen Bonding Dihydropteroate Synthase Quinoxalines Levofloxacin Yersinia pestis
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