AIMC Topic: Levofloxacin

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The application of design of experiments and artificial neural networks in the evaluation of the impact of acidic conditions on cloud point extraction.

Journal of chromatography. A Jan 17, 2025
This study aimed to analyze the impact of acidic conditions on the recovery of ciprofloxacin and levofloxacin for cloud point extraction with the Design of Experiments and Artificial Neural Networks. The design included 27 experiments featuring three...
Temperature Reproducibility of Results Ciprofloxacin Neural Networks, Computer Sodium Chloride Chemical Fractionation Levofloxacin Hydrochloric Acid Hydrogen-Ion Concentration Polyethylene Glycols Chromatography, High Pressure Liquid
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Bloodstream Infections in Childhood Acute Myeloid Leukemia and Machine Learning Models: A Single-institutional Analysis.

Journal of pediatric hematology/oncology Oct 22, 2024
Childhood acute myeloid leukemia (AML) requires intensive chemotherapy, which may result in life-threatening bloodstream infections (BSIs). This study evaluated whether machine learning (ML) could predict BSI using electronic medical records. All chi...
Male Levofloxacin Infant Cytarabine Adolescent Retrospective Studies Humans Child, Preschool Machine Learning Child Female Bacteremia Leukemia, Myeloid, Acute
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Innovative strategies against superbugs: Developing an AI-CDSS for precise Stenotrophomonas maltophilia treatment.

Journal of global antimicrobial resistance Jun 22, 2024
OBJECTIVES: The World Health Organization named Stenotrophomonas maltophilia (SM) a critical multi-drug resistant threat, necessitating rapid diagnostic strategies. Traditional culturing methods require up to 96 h, including 72 h for bacterial growth...
Artificial Intelligence Machine Learning Anti-Bacterial Agents Humans Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Gram-Negative Bacterial Infections Levofloxacin Trimethoprim, Sulfamethoxazole Drug Combination Microbial Sensitivity Tests Drug Resistance, Multiple, Bacterial Decision Support Systems, Clinical Stenotrophomonas maltophilia
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Application of machine learning in the study of cobalt-based oxide catalysts for antibiotic degradation: An innovative reverse synthesis strategy.

Journal of hazardous materials Apr 16, 2024
This study addresses antibiotic pollution in global water bodies by integrating machine learning and optimization algorithms to develop a novel reverse synthesis strategy for inorganic catalysts. We meticulously analyzed data from 96 studies, ensurin...
Norfloxacin Levofloxacin Algorithms Anti-Bacterial Agents Water Pollutants, Chemical Oxides Catalysis Cobalt Machine Learning
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Rapid discrimination and ratio quantification of mixed antibiotics in aqueous solution through integrative analysis of SERS spectra via CNN combined with NN-EN model.

Journal of advanced research Mar 24, 2024
INTRODUCTION: Abusing antibiotic residues in the natural environment has become a severe public health and ecological environmental problem. The side effects of its biochemical and physiological consequences are severe. To avoid antibiotic contaminat...
Levofloxacin Doxycycline Spectrum Analysis, Raman Water Pollutants, Chemical Ciprofloxacin Neural Networks, Computer Deep Learning Algorithms Water Anti-Bacterial Agents
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Design, synthesis, antibacterial evaluation and molecular docking studies of some new quinoxaline derivatives targeting dihyropteroate synthase enzyme.

Bioorganic chemistry Dec 5, 2017
Development of new antimicrobial agents is a good solution to overcome drug-resistance problems. From this perspective, new quinoxaline derivatives bearing various bioactive heterocyclic moieties (thiadiazoles, oxadiazoles, pyrazoles and thiazoles) w...
Yersinia pestis Dihydropteroate Synthase Quinoxalines Levofloxacin Anti-Bacterial Agents Microbial Sensitivity Tests Molecular Structure Molecular Docking Simulation Protein Binding Hydrophobic and Hydrophilic Interactions Drug Design Structure-Activity Relationship Gram-Negative Bacteria Catalytic Domain Gram-Positive Bacteria Hydrogen Bonding
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Characterization of digital camera-based UV illumination fluorescent imaging for concentration measurement with limit of detection, specificity and precision.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Jul 1, 2025
Nowadays the increased need for pharmaceutics requires fast, cheap and reliable quality control systems to investigate the final product's quality. The generally used methods like high-pressure liquid chromatography (HPLC) and other coupled technique...
Levofloxacin Tablets Ultraviolet Rays Optical Imaging Reproducibility of Results Limit of Detection
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Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Nov 28, 2018
BACKGROUND: Levofloxacin is used for the treatment of multidrug-resistant tuberculosis; however the optimal dose is unknown.
Humans Artificial Intelligence Algorithms Microbial Sensitivity Tests Drug Resistance, Multiple, Bacterial Monte Carlo Method Tuberculosis, Pulmonary Levofloxacin Mycobacterium tuberculosis Drug Therapy, Combination Sputum Antitubercular Agents Tuberculosis, Multidrug-Resistant
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[Synthesis and biological evaluation of novel pleuromutilin derivatives with nitrogen-containing heterocycles as antibacterial agents].

Yao xue xue bao = Acta pharmaceutica Sinica Oct 1, 2015
A series of new pleuromutilins derivatives were designed and synthesized through coupling 2-aminothiazole ring of WL001 with different nitrogen-containing substituted heterocycles in the side chain. Their biological activities were evaluated against ...
Pleuromutilins Anti-Bacterial Agents Gram-Negative Bacteria Microbial Sensitivity Tests Structure-Activity Relationship Levofloxacin Diterpenes Amoxicillin Polycyclic Compounds Nitrogen
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