AIMC Topic: DNA-Binding Proteins

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Improving the prediction of DNA-protein binding by integrating multi-scale dense convolutional network with fault-tolerant coding.

Analytical biochemistry Aug 29, 2022
Accurate prediction of DNA-protein binding (DPB) is of great biological significance for studying the regulatory mechanism of gene expression. In recent years, with the rapid development of deep learning techniques, advanced deep neural networks have...
DNA-Binding Proteins Neural Networks, Computer Software Protein Binding DNA
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iDRBP-ECHF: Identifying DNA- and RNA-binding proteins based on extensible cubic hybrid framework.

Computers in biology and medicine Aug 13, 2022
Proteins interact with nucleic acids to regulate the life activities of organisms. Therefore, how to accurately and efficiently identify nucleic acid-binding proteins (NABPs) is particularly significant. Some sequence-based computational methods have...
Algorithms Computational Biology Machine Learning DNA-Binding Proteins Binding Sites RNA-Binding Proteins DNA
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IDRBP-PPCT: Identifying Nucleic Acid-Binding Proteins Based on Position-Specific Score Matrix and Position-Specific Frequency Matrix Cross Transformation.

IEEE/ACM transactions on computational biology and bioinformatics Aug 8, 2022
DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) are two important nucleic acid-binding proteins (NABPs), which play important roles in biological processes such as replication, translation and transcription of genetic material. Some prote...
Algorithms Computational Biology Databases, Protein DNA RNA-Binding Proteins Support Vector Machine Amino Acid Sequence DNA-Binding Proteins Position-Specific Scoring Matrices
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Research on DNA-Binding Protein Identification Method Based on LSTM-CNN Feature Fusion.

Computational and mathematical methods in medicine Jun 2, 2022
Protein is closely related to life activities. As a kind of protein, DNA-binding protein plays an irreplaceable role in life activities. Therefore, it is very important to study DNA-binding protein, which is a subject worthy of study. Although tradit...
Neural Networks, Computer Machine Learning DNA-Binding Proteins Humans Amino Acid Sequence
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DeepDNAbP: A deep learning-based hybrid approach to improve the identification of deoxyribonucleic acid-binding proteins.

Computers in biology and medicine Mar 30, 2022
Accurate identification of DNA-binding proteins (DBPs) is critical for both understanding protein function and drug design. DBPs also play essential roles in different kinds of biological activities such as DNA replication, repair, transcription, and...
Position-Specific Scoring Matrices Deep Learning Computational Biology DNA DNA-Binding Proteins Neural Networks, Computer
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Application of DNA-Binding Protein Prediction Based on Graph Convolutional Network and Contact Map.

BioMed research international Jan 17, 2022
DNA contains the genetic information for the synthesis of proteins and RNA, and it is an indispensable substance in living organisms. DNA-binding proteins are an enzyme, which can bind with DNA to produce complex proteins, and play an important role ...
DNA-Binding Proteins Neural Networks, Computer
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FTWSVM-SR: DNA-Binding Proteins Identification via Fuzzy Twin Support Vector Machines on Self-Representation.

Interdisciplinary sciences, computational life sciences Nov 6, 2021
Due to the high cost of DNA-binding proteins (DBPs) detection, many machine learning algorithms (ML) have been utilized to large-scale process and detect DBPs. The previous methods took no count of the processing of noise samples. In this study, a fu...
Machine Learning DNA-Binding Proteins Algorithms Support Vector Machine
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Multi-Scale Capsule Network for Predicting DNA-Protein Binding Sites.

IEEE/ACM transactions on computational biology and bioinformatics Oct 7, 2021
Discovering DNA-protein binding sites, also known as motif discovery, is the foundation for further analysis of transcription factors (TFs). Deep learning algorithms such as convolutional neural networks (CNN) have been introduced to motif discovery ...
Deep Learning Protein Binding Algorithms Binding Sites Sequence Analysis, Protein Computational Biology Transcription Factors Chromatin Immunoprecipitation Sequencing DNA-Binding Proteins
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RF-SVM: Identification of DNA-binding proteins based on comprehensive feature representation methods and support vector machine.

Proteins Sep 9, 2021
Protein-DNA interactions play an important role in biological progress, such as DNA replication, repair, and modification processes. In order to have a better understanding of its functions, the one of the most important steps is the identification o...
Databases, Protein DNA Computational Biology Support Vector Machine DNA-Binding Proteins
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DeepDRBP-2L: A New Genome Annotation Predictor for Identifying DNA-Binding Proteins and RNA-Binding Proteins Using Convolutional Neural Network and Long Short-Term Memory.

IEEE/ACM transactions on computational biology and bioinformatics Aug 6, 2021
DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) are two kinds of crucial proteins, which are associated with various cellule activities and some important diseases. Accurate identification of DBPs and RBPs facilitate both theoretical rese...
RNA-Binding Proteins DNA-Binding Proteins Algorithms Molecular Sequence Annotation Neural Networks, Computer Genomics
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