AIMC Topic: DNA

Clear Filters Showing 131 to 140 of 457 articles

SCP4ssd: A Serverless Platform for Nucleotide Sequence Synthesis Difficulty Prediction Using an AutoML Model.

Genes Feb 28, 2023
DNA synthesis is widely used in synthetic biology to construct and assemble sequences ranging from short RBS to ultra-long synthetic genomes. Many sequence features, such as the GC content and repeat sequences, are known to affect the synthesis diffi...
Base Composition Escherichia coli Base Sequence DNA Machine Learning
View on PubMed DOI

A Grid Search-Based Multilayer Dynamic Ensemble System to Identify DNA N4-Methylcytosine Using Deep Learning Approach.

Genes Feb 25, 2023
DNA (Deoxyribonucleic Acid) N4-methylcytosine (4mC), a kind of epigenetic modification of DNA, is important for modifying gene functions, such as protein interactions, conformation, and stability in DNA, as well as for the control of gene expression ...
Animals Deep Learning DNA Epigenesis, Genetic
View on PubMed DOI

Nucleic Acid Quantification by Multi-Frequency Impedance Cytometry and Machine Learning.

Biosensors Feb 24, 2023
Determining nucleic acid concentrations in a sample is an important step prior to proceeding with downstream analysis in molecular diagnostics. Given the need for testing DNA amounts and its purity in many samples, including in samples with very smal...
Neural Networks, Computer Machine Learning Microfluidics DNA Electric Impedance
View on PubMed DOI

Deep reinforcement learning-based pairwise DNA sequence alignment method compatible with embedded edge devices.

Scientific reports Feb 16, 2023
Sequence alignment is an essential component of bioinformatics, for identifying regions of similarity that may indicate functional, structural, or evolutionary relationships between the sequences. Genome-based diagnostics relying on DNA sequencing ha...
Algorithms Sequence Alignment Neural Networks, Computer DNA Computers
View on PubMed DOI

SENIES: DNA Shape Enhanced Two-Layer Deep Learning Predictor for the Identification of Enhancers and Their Strength.

IEEE/ACM transactions on computational biology and bioinformatics Feb 3, 2023
Identifying enhancers is a critical task in bioinformatics due to their primary role in regulating gene expression. For this reason, various computational algorithms devoted to enhancer identification have been put forward over the years. More featur...
DNA Enhancer Elements, Genetic Algorithms Computational Biology Deep Learning
View on PubMed DOI

iDRBP-EL: Identifying DNA- and RNA- Binding Proteins Based on Hierarchical Ensemble Learning.

IEEE/ACM transactions on computational biology and bioinformatics Feb 3, 2023
Identification of DNA-binding proteins (DBPs) and RNA-binding proteins (RBPs) from the primary sequences is essential for further exploring protein-nucleic acid interactions. Previous studies have shown that machine-learning-based methods can efficie...
Machine Learning Deep Learning Algorithms RNA Computational Biology DNA-Binding Proteins DNA RNA-Binding Proteins
View on PubMed DOI

Laplacian Regularized Sparse Representation Based Classifier for Identifying DNA N4-Methylcytosine Sites via L-Matrix Norm.

IEEE/ACM transactions on computational biology and bioinformatics Feb 3, 2023
N4-methylcytosine (4mC) is one of important epigenetic modifications in DNA sequences. Detecting 4mC sites is time-consuming. The computational method based on machine learning has provided effective help for identifying 4mC. To further improve the p...
DNA Epigenesis, Genetic Algorithms Machine Learning
View on PubMed DOI

I-DNAN6mA: Accurate Identification of DNA N-Methyladenine Sites Using the Base-Pairing Map and Deep Learning.

Journal of chemical information and modeling Feb 1, 2023
The recent discovery of numerous DNA N-methyladenine (6mA) sites has transformed our perception about the roles of 6mA in living organisms. However, our ability to understand them is hampered by our inability to identify 6mA sites rapidly and cost-ef...
Animals Deep Learning Drosophila melanogaster Arabidopsis DNA DNA Methylation
View on PubMed DOI

Molecular Computation for Molecular Classification.

Advanced biology Jan 29, 2023
DNA as an informational polymer has, for the past 30 years, progressively become an essential molecule to rationally build chemical reaction networks endowed with powerful signal-processing capabilities. Whether influenced by the silicon world or ins...
Logic Computers, Molecular DNA Neural Networks, Computer Signal Processing, Computer-Assisted
View on PubMed DOI

A universal deep-learning model for zinc finger design enables transcription factor reprogramming.

Nature biotechnology Jan 26, 2023
CysHis zinc finger (ZF) domains engineered to bind specific target sequences in the genome provide an effective strategy for programmable regulation of gene expression, with many potential therapeutic applications. However, the structurally intricate...
Transcription Factors Zinc Fingers Gene Expression Regulation DNA Humans Deep Learning
View on PubMed DOI
Popular Topics
Recent Journals