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Fluorescent Antibody Technique, Indirect

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Benchmarking human epithelial type 2 interphase cells classification methods on a very large dataset.

Artificial intelligence in medicine
OBJECTIVE: This paper presents benchmarking results of human epithelial type 2 (HEp-2) interphase cell image classification methods on a very large dataset. The indirect immunofluorescence method applied on HEp-2 cells has been the gold standard to i...

HEp-2 Cell Image Classification With Deep Convolutional Neural Networks.

IEEE journal of biomedical and health informatics
Efficient Human Epithelial-2 cell image classification can facilitate the diagnosis of many autoimmune diseases. This paper proposes an automatic framework for this classification task, by utilizing the deep convolutional neural networks (CNNs) which...

Deep learning based HEp-2 image classification: A comprehensive review.

Medical image analysis
Classification of HEp-2 cell patterns plays a significant role in the indirect immunofluorescence test for identifying autoimmune diseases in the human body. Many automatic HEp-2 cell classification methods have been proposed in recent years, amongst...

Deep Learning Fuzzy Inference: An Interpretable Model for Detecting Indirect Immunofluorescence Patterns Associated with Nasopharyngeal Cancer.

The American journal of pathology
The detection of serum Epstein-Barr virus antibodies by immunofluorescence assay (IFA) is considered the gold standard screening test for nasopharyngeal cancer (NPC) in high-risk populations. Given the high survival rate after early detection in asym...

A Multi-task learning U-Net model for end-to-end HEp-2 cell image analysis.

Artificial intelligence in medicine
Antinuclear Antibody (ANA) testing is pivotal to help diagnose patients with a suspected autoimmune disease. The Indirect Immunofluorescence (IIF) microscopy performed with human epithelial type 2 (HEp-2) cells as the substrate is the reference metho...

Comparison of artificial intelligence applications and commercial system performances using selected ANA IIF images.

Immunologic research
Accurate and accessible classification of anti-nuclear antibodies (ANA) through indirect immunofluorescence (IIF) imaging is crucial for diagnosing autoimmune diseases. However, many laboratories, particularly those with limited resources, lack acces...