AIMC Topic: Machine Learning

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deepNEC: a novel alignment-free tool for the identification and classification of nitrogen biochemical network-related enzymes using deep learning.

Briefings in bioinformatics
Nitrogen is essential for life and its transformations are an important part of the global biogeochemical cycle. Being an essential nutrient, nitrogen exists in a range of oxidation states from +5 (nitrate) to -3 (ammonium and amino-nitrogen), and it...

A review of machine learning approaches for drug synergy prediction in cancer.

Briefings in bioinformatics
Combinational pharmacotherapy with the synergistic/additive effect is a powerful treatment strategy for complex diseases such as malignancies. Identifying synergistic combinations with various compounds and structures requires testing a large number ...

SPLDExtraTrees: robust machine learning approach for predicting kinase inhibitor resistance.

Briefings in bioinformatics
Drug resistance is a major threat to the global health and a significant concern throughout the clinical treatment of diseases and drug development. The mutation in proteins that is related to drug binding is a common cause for adaptive drug resistan...

Photonics-enabled spiking timing-dependent convolutional neural network for real-time image classification.

Optics express
A photonics-enabled spiking timing-dependent convolutional neural network (CNN) is proposed by manipulating photonics multidimensional parameters in terms of wavelength, temporal and spatial, which breaks the traditional CNN architecture mapping from...

Quantitative phase imaging based on model transfer learning.

Optics express
Convolutional neural networks have been widely used in optical information processing and the generalization ability of the network depends greatly on the scale and diversity of the datasets, however, the acquisition of mass datasets and later annota...

[Labelling, segmentation and application of neural network based on machine learning of three-dimensional intraoral anatomical features].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
With the advent of the era of big data, artificial intelligence based on machine learning, especially artificial neural network has rapidly developed and applicated in the field of stomatology, owning huge potential in segmentation and labelling of t...

Machine Learning Hidden Symmetries.

Physical review letters
We present an automated method for finding hidden symmetries, defined as symmetries that become manifest only in a new coordinate system that must be discovered. Its core idea is to quantify asymmetry as violation of certain partial differential equa...

Trainability of Dissipative Perceptron-Based Quantum Neural Networks.

Physical review letters
Several architectures have been proposed for quantum neural networks (QNNs), with the goal of efficiently performing machine learning tasks on quantum data. Rigorous scaling results are urgently needed for specific QNN constructions to understand whi...

AggMapNet: enhanced and explainable low-sample omics deep learning with feature-aggregated multi-channel networks.

Nucleic acids research
Omics-based biomedical learning frequently relies on data of high-dimensions (up to thousands) and low-sample sizes (dozens to hundreds), which challenges efficient deep learning (DL) algorithms, particularly for low-sample omics investigations. Here...

Predicting Future Mobility Limitation in Older Adults: A Machine Learning Analysis of Health ABC Study Data.

The journals of gerontology. Series A, Biological sciences and medical sciences
BACKGROUND: Mobility limitation in older adults is common and associated with poor health outcomes and loss of independence. Identification of at-risk individuals remains challenging because of time-consuming clinical assessments and limitations of s...