AIMC Topic: Machine Learning

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Machine learning on thyroid disease: a review.

Frontiers in bioscience (Landmark edition)
This study reviews the recent progress of machine learning for the early diagnosis of thyroid disease. Based on the results of this review, different machine learning methods would be appropriate for different types of data for the early diagnosis of...

Machine Learning-based Prediction Models for Diagnosis and Prognosis in Inflammatory Bowel Diseases: A Systematic Review.

Journal of Crohn's & colitis
BACKGROUND AND AIMS: There is increasing interest in machine learning-based prediction models in inflammatory bowel diseases [IBD]. We synthesised and critically appraised studies comparing machine learning vs traditional statistical models, using ro...

How to remove or control confounds in predictive models, with applications to brain biomarkers.

GigaScience
BACKGROUND: With increasing data sizes and more easily available computational methods, neurosciences rely more and more on predictive modeling with machine learning, e.g., to extract disease biomarkers. Yet, a successful prediction may capture a con...

Potential of edge machine learning for instrumentation.

Applied optics
New developments in radiation and photonic detectors improve resolution, sensitivity, size, and rate, all of which contribute to a gigantic increase in the data production rate. Moving data analysis and compression adjacent or even embedded within th...

Multi-variable AUC for sifting complementary features and its biomedical application.

Briefings in bioinformatics
Although sifting functional genes has been discussed for years, traditional selection methods tend to be ineffective in capturing potential specific genes. First, typical methods focus on finding features (genes) relevant to class while irrelevant to...

Persistent spectral based ensemble learning (PerSpect-EL) for protein-protein binding affinity prediction.

Briefings in bioinformatics
Protein-protein interactions (PPIs) play a significant role in nearly all cellular and biological activities. Data-driven machine learning models have demonstrated great power in PPIs. However, the design of efficient molecular featurization poses a ...

SVPath: an accurate pipeline for predicting the pathogenicity of human exon structural variants.

Briefings in bioinformatics
Although there are a large number of structural variations in the chromosomes of each individual, there is a lack of more accurate methods for identifying clinical pathogenic variants. Here, we proposed SVPath, a machine learning-based method to pred...

Predicting protein-membrane interfaces of peripheral membrane proteins using ensemble machine learning.

Briefings in bioinformatics
Abnormal protein-membrane attachment is involved in deregulated cellular pathways and in disease. Therefore, the possibility to modulate protein-membrane interactions represents a new promising therapeutic strategy for peripheral membrane proteins th...

Vec2image: an explainable artificial intelligence model for the feature representation and classification of high-dimensional biological data by vector-to-image conversion.

Briefings in bioinformatics
Feature representation and discriminative learning are proven models and technologies in artificial intelligence fields; however, major challenges for machine learning on large biological datasets are learning an effective model with mechanistical ex...