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Molecular Biology

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An Extended SNOMED CT Concept Model for Observations in Molecular Genetics.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Molecular genetics laboratory reports are multiplying and increasingly of clinical importance in diagnosis and treatment of cancer, infectious disease and managing of public health. Little of this data is structured or maintained in the EHR in format...

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Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Molecular biology is based on two great discoveries: the first is that genes carry hereditary information in the form of linear sequences of nucleotides; the second is that in protein synthesis a sequence of nucleotides is translated into a sequence ...

Conceptual Challenges in the Theoretical Foundations of Systems Biology.

Methods in molecular biology (Clifton, N.J.)
In the last decade, Systems Biology has emerged as a conceptual and explanatory alternative to reductionist-based approaches in molecular biology. However, the foundations of this new discipline need to be fleshed out more carefully. In this paper, w...

MAPLE (modular automated platform for large-scale experiments), a robot for integrated organism-handling and phenotyping.

eLife
Lab organisms are valuable in part because of large-scale experiments like screens, but performing such experiments over long time periods by hand is arduous and error-prone. Organism-handling robots could revolutionize large-scale experiments in the...

Machine learning approaches and their current application in plant molecular biology: A systematic review.

Plant science : an international journal of experimental plant biology
Machine learning (ML) is a field of artificial intelligence that has rapidly emerged in molecular biology, thus allowing the exploitation of Big Data concepts in plant genomics. In this context, the main challenges are given in terms of how to analyz...