AIMC Topic: Molecular Biology

Clear Filters Showing 1 to 10 of 25 articles

Artificial intelligence in molecular biology.

Molecular cell
In recent years, computational methods and artificial intelligence approaches have proven uniquely suited for studying patterns in molecular biology. In this focus issue, we spoke with researchers about using these tools to address various biological...

Comprehensive Analysis of Immune Infiltration and Key Genes in Peri-Implantitis Using Bioinformatics and Molecular Biology Approaches.

Medical science monitor : international medical journal of experimental and clinical research
BACKGROUND Peri-implantitis is the main cause of failure of implant treatment, and there is little research on its molecular mechanism. This study aimed to identify key biomarkers and immune infiltration of peri-implantitis using a bioinformatics met...

AI interprets the Central Dogma and Genetic Code.

Trends in biochemical sciences
Generative artificial intelligence (AI) is a burgeoning field with widespread applications, including in science. Here, we explore two paradigms that provide insight into the capabilities and limitations of Chat Generative Pre-trained Transformer (Ch...

Biomolecular NMR in the AI-assisted structural biology era: Old tricks and new opportunities.

Biochimica et biophysica acta. Proteins and proteomics
Over the last 40 years nuclear magnetic resonance (NMR) spectroscopy has established itself as one of the most versatile techniques for the characterization of biomolecules, especially proteins. Given the molecular size limitations of NMR together wi...

Protein complexes in cells by AI-assisted structural proteomics.

Molecular systems biology
Accurately modeling the structures of proteins and their complexes using artificial intelligence is revolutionizing molecular biology. Experimental data enable a candidate-based approach to systematically model novel protein assemblies. Here, we use ...

An RNA-based theory of natural universal computation.

Journal of theoretical biology
Life is confronted with computation problems in a variety of domains including animal behavior, single-cell behavior, and embryonic development. Yet we currently do not know of a naturally existing biological system that is capable of universal compu...

The AlphaFold Database of Protein Structures: A Biologist's Guide.

Journal of molecular biology
AlphaFold, the deep learning algorithm developed by DeepMind, recently released the three-dimensional models of the whole human proteome to the scientific community. Here we discuss the advantages, limitations and the still unsolved challenges of the...