AIMC Topic: Morphogenesis

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Deep neural net tracking of human pluripotent stem cells reveals intrinsic behaviors directing morphogenesis.

Stem cell reports May 11, 2021
Lineage tracing is a powerful tool in developmental biology to interrogate the evolution of tissue formation, but the dense, three-dimensional nature of tissue limits the assembly of individual cell trajectories into complete reconstructions of devel...
Humans Neural Networks, Computer Cells, Cultured Image Processing, Computer-Assisted Cell Movement Cell Differentiation Cell Count Bone Morphogenetic Protein 4 Smad Proteins Cell Lineage Cell Tracking Induced Pluripotent Stem Cells Morphogenesis
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Prediction of Growth Factor-Dependent Cleft Formation During Branching Morphogenesis Using A Dynamic Graph-Based Growth Model.

IEEE/ACM transactions on computational biology and bioinformatics Jan 1, 2016
This study considers the problem of describing and predicting cleft formation during the early stages of branching morphogenesis in mouse submandibular salivary glands (SMG) under the influence of varied concentrations of epidermal growth factors (EG...
Female Animals Mice Systems Biology Models, Statistical Unsupervised Machine Learning Models, Biological Monte Carlo Method Salivary Glands Morphogenesis
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