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Natriuretic Peptide, C-Type

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Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions.

European heart journal. Cardiovascular pharmacotherapy 27340557
AIMS: Cenderitide is a novel dual natriuretic peptide (NP) receptor chimeric peptide activator, which targets the particulate guanylyl cyclase B (pGC-B) receptor and pGC-A unlike native NPs. Cenderitide was engineered to retain the anti-fibrotic prop...
Animals Cyclic GMP Dendroaspis Dogs Drug Design Glomerular Filtration Rate HEK293 Cells Humans Kidney Function Tests Male Natriuretic Agents Natriuretic Peptide, C-Type Natriuretic Peptides Receptors, Atrial Natriuretic Factor Renal Agents Snake Venoms Structure-Activity Relationship
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