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Snake Venoms

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Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions.

European heart journal. Cardiovascular pharmacotherapy
AIMS: Cenderitide is a novel dual natriuretic peptide (NP) receptor chimeric peptide activator, which targets the particulate guanylyl cyclase B (pGC-B) receptor and pGC-A unlike native NPs. Cenderitide was engineered to retain the anti-fibrotic prop...

A comparative study of protein structure prediction tools for challenging targets: Snake venom toxins.

Toxicon : official journal of the International Society on Toxinology
Protein structure determination is a critical aspect of biological research, enabling us to understand protein function and potential applications. Recent advances in deep learning and artificial intelligence have led to the development of several pr...

AI-designed miniproteins neutralize snake toxins.

Science (New York, N.Y.)
Scientists are turning to AI to make antivenoms cheaper, faster, and more effective.