AI Medical Compendium Topic

Explore the latest research on artificial intelligence and machine learning in medicine.

Cyclic GMP

Showing 1 to 3 of 3 articles

Clear Filters

Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-B/p65 Signaling in Chronic Radiculitis Rats.

Pain research & management
BACKGROUND: Oxygen/ozone therapy is a minimally invasive technique for the treatment of radiculitis from lumbar disc herniation. This study aimed at investigating whether intrathecal administration of low-concentration oxygen/ozone could attenuate ch...

Cenderitide: structural requirements for the creation of a novel dual particulate guanylyl cyclase receptor agonist with renal-enhancing in vivo and ex vivo actions.

European heart journal. Cardiovascular pharmacotherapy
AIMS: Cenderitide is a novel dual natriuretic peptide (NP) receptor chimeric peptide activator, which targets the particulate guanylyl cyclase B (pGC-B) receptor and pGC-A unlike native NPs. Cenderitide was engineered to retain the anti-fibrotic prop...

Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network.

PLoS computational biology
Bacteria of many species rely on a simple molecule, the intracellular secondary messenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to make a vital choice: whether to stay in one place and form a biofilm, or to leave it in search...