AIMC Topic: Phosphodiesterase Inhibitors

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Immediate post-operative PDE5i therapy improves early erectile function outcomes after robot assisted radical prostatectomy (RARP).

Journal of robotic surgery Feb 8, 2021
To assess whether the timing of post-operative Phosphodiesterase Inhibitor (PDE5i) therapy after Robot-Assisted Radical Prostatectomy (RARP) is associated with a change in early erectile function (EF) outcomes, continence or safety outcomes. Data wer...
Humans Male Treatment Outcome Recovery of Function Robotics Robotic Surgical Procedures Prostatectomy Erectile Dysfunction Urinary Incontinence Phosphodiesterase Inhibitors
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Gaussian Process Regression Models for the Prediction of Hydrogen Bond Acceptor Strengths.

Molecular informatics Nov 25, 2018
We present two approaches for the computation of hydrogen bond acceptor strengths, one by machine-learning and one by a composite quantum-mechanical protocol, both based on the well-established pK scale and dataset. The QM calculations after a necess...
Machine Learning Inhibitory Concentration 50 Linear Models Databases, Chemical Quantitative Structure-Activity Relationship Hydrogen Bonding Normal Distribution Phosphodiesterase Inhibitors
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