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Data fusion strategies for performance improvement of a Process Analytical Technology platform consisting of four instruments: An electrospinning case study.

International journal of pharmaceutics 31252149
The aim of this work was to develop a PAT platform consisting of four complementary instruments for the characterization of electrospun amorphous solid dispersions with meloxicam. The investigated methods, namely NIR spectroscopy, Raman spectroscopy,...
Colorimetry Meloxicam Microscopy Neural Networks, Computer Photography Powder Diffraction Spectroscopy, Near-Infrared Spectrum Analysis, Raman Technology, Pharmaceutical X-Ray Diffraction
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Combining High-Throughput Screening and Machine Learning to Predict the Formation of Both Binary and Ternary Amorphous Solid Dispersion Formulations for Early Drug Discovery and Development.

Pharmaceutical research 40180767
OBJECTIVE: Amorphous solid dispersion (ASD) is widely utilized to enhance the solubility and bioavailability of water-insoluble drugs. However, conventional experimental approaches for ASD development are often resource-intensive and time-consuming. ...
Algorithms Chemistry, Pharmaceutical Crystallization Drug Compounding Drug Development Drug Discovery High-Throughput Screening Assays Machine Learning Powder Diffraction Solubility Support Vector Machine X-Ray Diffraction
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