Recently, pharmaceutical cocrystal technology has garnered considerable global attention because of its innovativeness and environmental sustainability. This technology effectively enhances the bioavailability of poorly soluble drugs and optimizes th...
Journal of materials science. Materials in medicine
Nov 21, 2025
Metal oxide nanomaterials play a central role in biomedical applications due to their unique physicochemical properties. In particular, various treatment methods such as drug delivery, hyperthermia therapy, radiation, and chemotherapy are used for th...
International journal of pharmaceutics
Oct 23, 2025
Understanding the molecular mechanisms of drug coamorphization remains a key challenge in solid-state pharmaceutics. This study presents a molecular level strategy for designing drug-drug coamorphous systems (CAMs) of apremilast (APR) and aceclofenac...
Ciprofloxacin (CFX) is a potent antibiotic for respiratory infections, but its poor solubility and high crystallinity limit its effectiveness in dry powder inhaler (DPI) delivery. Although soluble forms such as CFX hydrochloride are available, their ...
Journal of chemical information and modeling
Sep 22, 2025
The indexing of powder X-ray diffraction (PXRD) in unknown structure determinations is a critical yet challenging step in crystallography, particularly for low-symmetry systems (e.g., monoclinic, triclinic) and/or large unit cell systems ( > 1000 Å)...
The hydrothermal-calcination technique was used to modify raw sand with silver (Ag) at different weight percentages: 2%, 5%, and 10% using silver nitrate. The raw and sand-coated Ag nanoparticle samples were analyzed using various techniques, includi...
OBJECTIVE: Amorphous solid dispersion (ASD) is widely utilized to enhance the solubility and bioavailability of water-insoluble drugs. However, conventional experimental approaches for ASD development are often resource-intensive and time-consuming. ...
International journal of biological macromolecules
Mar 2, 2025
The increasing demand for sustainable and eco-friendly materials has spurred significant interest in natural fibers as alternatives to synthetic reinforcements in composite applications. This study aims to explore the potential of Lablab purpureus fi...
Advanced deep learning and statistical methods can predict structural models for RNA molecules. However, RNAs are flexible, and it remains difficult to describe their macromolecular conformations in solutions where varying conditions can induce confo...
The integration of natural fibers into Fiber Reinforced Polymers (FRPs) has emerged as a promising avenue for sustainable and high-performance composite materials. Natural fibers, derived from plants, offer notable advantages such as renewability, lo...
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